Carbetalol 12.5 mg Tablet (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may be sufficient to achieve the desired effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased up to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard therapy (conventional treatment for chronic heart failure, typically including an ACE inhibitor, a diuretic, and a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended that this medicine be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used in certain patients. For example, it should be avoided in patients with allergies to this drug or its ingredients, patients with cardiogenic shock, those with conduction problems in the heart, pulmonary heart disease, patients with metabolic acidosis due to diabetes, etc. Additionally, it is not recommended for women who are pregnant or breastfeeding, or for patients with respiratory diseases such as asthma or chronic obstructive pulmonary disease. Patients with genetic lactose intolerance should not take this medication. This drug should be used cautiously in patients with diabetes, those with a significant history of allergies, patients with hypotension, those with impaired kidney or liver function, and elderly patients. Blood pressure, heart rate, kidney and liver function should be regularly monitored under the instructions of a physician during treatment. Side effects such as dizziness, fatigue, headache, decreased heart rate, hypotension, respiratory distress, and skin rash may occur. If symptoms worsen, consult a physician immediately. Additionally, stopping this medication suddenly can worsen cardiac symptoms, so any discontinuation or dose adjustment must be done gradually and under the guidance of a physician. This medication may interact with other drugs, so if you are taking other medications such as antihypertensives, antidiabetics, antidepressants, analgesics, and anesthetics, be sure to inform your doctor or pharmacist. If pregnant or breastfeeding, this medication should not be taken as it may affect the fetus or newborn. The safety and effectiveness for children and adolescents have not been sufficiently established, so use is not recommended. Elderly patients may have decreased liver function and should start at a low dose and be closely monitored. In cases of overdose, severe hypotension, decreased heart rate, decreased cardiac function, shock, and respiratory distress may occur, necessitating immediate medical attention and emergency treatment. This drug may discolor when exposed to light, so it should be stored in a container that prevents light exposure and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucination
• confusion
• depression
• sleep disturbance
• nightmare
• psychosis

This medication is light-sensitive and should be stored in a container that does not allow light in. Additionally, it is recommended to store the medication at room temperature between 1°C and 30°C. This will help maintain the medication's effectiveness for a longer period.

Appearance

Brownish-red round tablet

Package unit

90 tablets (10 tablets/PTP × 9)