IYON Clarithromycin Tablet 500 mg

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half, i.e., 250mg (potency) once daily or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in specific patients. For example, patients allergic to any components in this medication or who have had adverse reactions to similar classes of antibiotics should avoid it. Additionally, it should not be administered to patients currently taking certain heart-related medications or those with a history of prolonged QT interval cardiac disease, severe liver impairments, or significantly reduced kidney function. Pregnant or nursing women and patients with central nervous system infections should avoid using this medication for safety reasons. This drug may affect liver and kidney function; hence, it should be used cautiously in patients with liver dysfunction or renal failure, especially among the elderly or patients with heart disease. Since there can be allergic reactions or severe side effects while using this drug, if symptoms such as shortness of breath, rash, severe skin abnormalities, gastrointestinal distress, or neurological symptoms occur, administration should be stopped immediately and consult a healthcare professional. This medication has many interactions with other drugs, particularly with those affecting the heart, medications metabolized by the liver, hypoglycemic agents, anticoagulants, and certain antibiotics, so it's important to inform a doctor or pharmacist when using them, as dose adjustments or monitoring may be necessary. Pregnant or nursing mothers should avoid this medication; if necessary, breastfeeding should be discontinued. Use in children under 12 is not recommended in tablet form, and caution is needed even in pediatric cases. Elderly patients may have increased drug concentrations due to decreased bodily function, and care should be taken in their administration; dose adjustment is required for severely reduced kidney function. Regular liver function tests, kidney function tests, and blood tests are required to detect any adverse reactions early and respond accordingly. In case of overdose, gastrointestinal disturbances or neurological symptoms may appear, thus the exact dosage should be followed as directed by a physician. This medication may have reduced absorption rates when used with specific preparations, so be cautious about the medications taken concurrently. For storage, keep in a tight container that blocks light and maintain a temperature between 15 degrees and 30 degrees Celsius. This will help preserve the drug's effectiveness and safety.

Shock, anaphylactic symptoms, respiratory distress, convulsions, redness, rashes, itching, urticaria, skin redness, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbances, loss of appetite, constipation, discoloration of stools, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, paresthesia, behavioral changes, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal stiffness, myopathy, elevated serum creatinine, elevated blood urea, nephritis, venous thrombophlebitis at injection site, pain at injection site, inflammation at injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, vasodilation, cardiac arrest, atrial fibrillation, QT prolongation on ECG, ectopic beats, palpitations, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura

This medication must be stored in a light-blocking, airtight container, maintaining a storage temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and safety.

Appearance

Yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle