Medication info
Clarithromycin Tablet (Chlorasine)

Clarithromycin Tablet (Chlorasine)

Prescription medicationTablet
Ingredient · strength
Clarithromycin›250mg / 1 tablet
Manufacturer / importer
Ajou Pharmaceutical Co., Ltd.
Appearance
Yellow oval film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201803806 · Approved 2018.09.27 · Insurance code 654005140

Summary

Main use
Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori eradication
Who uses it
Adults · Children
Adult dosage
○ Adults : The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections : Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer : For 14 days, administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).
Children's dosage
○ Children aged 12 years or older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

Ingredients

Manufacturer
Ajou Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori eradication

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • infections of the skin and soft tissues
  • mycobacterial infections
  • duodenal ulcers
View approved original text

This medication is effective against various bacterial infections. It is used for lower respiratory tract infections such as bronchitis and pneumonia, as well as upper respiratory tract infections such as pharyngitis and sinusitis. Additionally, it helps in treating infections of the skin and soft tissues. It is also effective against Mycobacterium infections, including those caused by Mycobacterium avium or intracellularis. The drug is used to eradicate Helicobacter pylori, which is one of the causes of duodenal ulcers. This medication is used to improve various bacterial infections.

Dosage and Administration

Adult dosage

○ Adults : The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections : Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer : For 14 days, administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).

Children's dosage

○ Children aged 12 years or older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

Precautions

This medication should not be administered to patients with certain medications or conditions. For example, those who are allergic to the ingredients of this medication or have specific heart conditions may face risks. It is necessary to adjust the dose or refrain from using this drug in patients with severely impaired liver or kidney function. Moreover, it is safer for pregnant or breastfeeding women to avoid this medication. This medicine may interact with various medications, so if you are taking other drugs, consult your doctor or pharmacist. Care must be taken when used with medications that may affect the heart, as it may exacerbate side effects. Rarely, during administration, allergic reactions or gastrointestinal disorders, liver function abnormalities, kidney problems, skin rashes, etc., may occur, and if any symptoms arise, immediate notification to healthcare personnel is necessary. When used for an extended period or repeatedly, resistant bacteria may develop; hence it is important to take it only for the appropriate duration as directed by a physician. Children, the elderly, and those with impaired liver or kidney function must be especially cautious when using this medication, and dosage adjustments may be necessary. This drug can cause dizziness or confusion that could affect driving or operating machinery, so caution is needed after taking it. In cases of overdose, gastrointestinal disorders or neurological symptoms may occur, and in such cases, seeking immediate medical attention for appropriate treatment is essential. This medication should be stored in a sealed container, protected from air and moisture, and stored at room temperature between 1 to 30 degrees Celsius.

Side effects

Shock, anaphylactic symptoms, difficulty breathing, convulsions, redness, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, bloating, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste alteration, loss of appetite, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, hearing disorder, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle spasms, musculoskeletal rigidity, myopathy, increased serum creatinine, elevated blood urea, nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture, at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.