Clarithon Tablets (Clarithromycin)

Adult dosage

○ Adults The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections Administer this drug 500mg (potency) twice daily. In this case, it should be administered in combination with other antimycobacterial drugs such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer Administer this drug 500mg (potency) 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults For children younger than 12 years, use clarithromycin dry syrup.

This medication should not be used in patients with certain medications or conditions. For example, it should not be administered to individuals who are allergic to its ingredients or have certain heart conditions, severe liver or kidney dysfunction. Pregnant or breastfeeding women should also avoid taking this medication. It may interact with other medications, so it is essential to inform your doctor or pharmacist about any other medications you are currently taking. Special caution is necessary when taken with drugs that may affect the heart or liver and kidneys. If any unusual symptoms or allergic reactions occur while taking this medication, discontinue it immediately and consult a medical professional. Dosage adjustments may be necessary for elderly patients or those with reduced liver or kidney function. This medication can cause various side effects such as gastrointestinal disturbances, skin rashes, and central nervous system symptoms, so symptoms should be closely monitored during use. Additionally, prolonged or repeated administration can lead to the development of resistant bacteria, so the prescribed duration and dosage must be strictly followed. Pregnant or breastfeeding women should avoid this medication whenever possible; if unavoidable, breastfeeding should be discontinued. This medication may require caution when driving or operating machinery due to its potential effects on activities, which should be acknowledged. In cases of overdose, gastrointestinal symptoms or central nervous system disturbances may occur, requiring immediate medical assistance. Finally, this medication should be stored away from direct sunlight and at room temperature; refrigeration is not recommended.

Shock, anaphylactic symptoms, dyspnea, seizures, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, dry mouth, tooth discoloration, pancreatitis, increased amylase, taste alterations, anorexia, constipation, discoloration of feces, pseudomembranous colitis, hemorrhagic colitis, fever, cough, dyspnea, chest X-ray abnormalities, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver function impairment, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, tinnitus, hearing impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal rigidity, myopathy, elevated blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature should be maintained between 1 degree and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle