Chantix 0.5 mg (Varenicline Salicylate)

Adult dosage

After dose titration over 1 week, administer 1 mg twice daily. Days 1–3: 0.5 mg once daily Days 4–7: 0.5 mg twice daily Day 8 until end of treatment: 1 mg twice daily For patients who cannot tolerate the adverse reactions of this medicine, the dose may be reduced temporarily or permanently. The treatment period with this medicine is 12 weeks. For patients who successfully quit smoking with the first 12 weeks of treatment, it is recommended that this medicine be administered for an additional 12 weeks to increase the likelihood of long-term abstinence. Administer this medicine for an additional 12 weeks for a total treatment period of 24 weeks. No dose adjustment is necessary in patients with mild (estimated creatinine clearance > 50 mL/min and ≤ 80 mL/min) to moderate (estimated creatinine clearance ≥ 30 mL/min and ≤ 50 mL/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 mL/min), the recommended starting dose of varenicline is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease undergoing hemodialysis, if well tolerated, a maximum dose of 0.5 mg once daily may be administered. No dose adjustment is necessary in patients with hepatic impairment. Because renal function is more likely to be decreased in elderly patients, caution should be exercised when selecting the dose, and monitoring renal function may be useful.

Children's dosage

Patients under 18 years of age: Use is not recommended because the safety and efficacy of this medicine have not been established in children.

This medication aids in quitting smoking and works on nicotine receptors in the brain to alleviate withdrawal symptoms that may arise during cessation. While taking this medication, significant mental health issues such as depression, anxiety, hallucinations, and suicidal thoughts or behaviors may occur. If such symptoms arise, discontinue use immediately and consult a doctor. Patients with hypersensitivity or allergy to this medication's components should not use it. Women who are pregnant or breastfeeding should use this medication cautiously and consult with a doctor regarding the potential effects on the fetus or baby. Common side effects that may occur while taking this medication include nausea, headache, insomnia, and abnormal dreams, which may persist for some patients. Be cautious when engaging in activities requiring attention, such as driving or operating machinery, as this medication may cause drowsiness or impair concentration. The risk of side effects may be higher in elderly patients with impaired kidney function, so dose adjustment and monitoring of kidney function are necessary. In case of overdose, there is no specific antidote, and appropriate treatment should be administered based on symptoms. Kidney dialysis may be beneficial. This medication has relatively few interactions with other drugs, but alcohol consumption may worsen side effects, so it is advisable to avoid it. While taking this medication and attempting to quit smoking, carefully monitor any physical or mental changes, and immediately consult medical personnel if abnormal symptoms appear.

• Suicidal thoughts
• suicidal behavior
• suicide
• changes in behavior or thoughts
• depression
• mania
• psychosis
• aggressive behavior
• hallucinations
• paranoia

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius. This helps maintain the medication's efficacy and safety over time.

Appearance

White or grayish-white, double-sided convex film-coated tablet

Package unit

11 tablets (11 tablets/PTP X 1)