Rosuvastatin Calcium Tablets 5mg

Adult dosage

This drug can be administered at any time of the day regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is usually 10 mg once daily, which most patients are adjusted to. The maintenance dose may be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient responses after 4 weeks or longer, and can be increased to a maximum of 20 mg per day.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dosage range is 5 mg to 20 mg once daily. The dosage should be adjusted according to individual treatment goals.

This drug should not be used in certain patients. It is contraindicated in patients with an allergy to the ingredients of this drug, persistent unexplained liver dysfunction, muscle diseases, patients taking certain medications, patients with severe renal impairment, pregnant or breastfeeding women, and women of childbearing age not using appropriate contraception. Additionally, high-dose use of this drug is prohibited in patients at high risk for muscle diseases. Patients with genetic lactose intolerance should also avoid taking this drug. This medication should be used cautiously in patients with impaired liver function or those consuming alcohol excessively, and it is recommended to repeat liver function tests before and during treatment. Muscle pain, myopathy, and, rarely, a severe muscle degradation condition called rhabdomyolysis may occur; any symptoms related to muscles should be immediately reported to a healthcare provider. If there is a significant increase in muscle enzyme levels, the medication should be discontinued, and it may be restarted after the symptoms improve based on the doctor's judgment. In cases of acute renal failure or severity, the administration of this drug should be stopped, and if severe muscle weakness symptoms arise, it should be stopped immediately. Caution should be exercised as this medication may increase plasma concentrations when combined with certain drugs, leading to a higher risk of muscle disease; consult with healthcare providers regarding concomitant medications. This medication should not be taken during pregnancy or breastfeeding, and women who may become pregnant should use appropriate contraceptive methods. There is no specific antidote for overdose, so treatment based on symptoms and monitoring of liver function and muscle enzyme levels is necessary. This medication does not significantly affect driving or machine operation, but caution is advised as dizziness may occur. Lastly, if any unusual symptoms appear, such as liver dysfunction, muscle pain, or skin rashes while taking this medication, inform healthcare providers immediately.

Serious side effects

Allergic reactions including hives and angioedema, rhabdomyolysis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms, jaundice, hepatitis, severe muscle weakness, ocular myasthenia, acute renal failure, oliguria, chest tightness, difficulty breathing, dyspnea, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• diarrhea
• thrombocytopenia

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature. Proper storage will help prolong the medication's effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets/Alu-Alu, 30 tablets/bottle, 300 tablets/bottle