Medication info

Metastine 24 mg Tablets (Betahistine Dihydrochloride)

Prescription medicationApproval withdrawn
Ingredient · strength
Betahistine Hydrochloride›Strength being verified
Manufacturer / importer
CMG Pharmaceutical Co., Ltd.
Appearance
Blue rectangular tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201801944 · Notified 2018.05.09

This product's status changed to Approval withdrawn on 2023.03.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of Ménière’s disease symptoms (dizziness, tinnitus, etc.)
Who uses it
Adults
Adult dosage
Adults: The initial dose is 16 mg of betahistine hydrochloride per dose, administered orally 3 times daily with meals. The usual maintenance dose is 24 ~ 48 mg of betahistine hydrochloride daily

Ingredients

Manufacturer
CMG Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of Ménière’s disease symptoms (dizziness, tinnitus, etc.)

  • Dizziness
  • tinnitus
  • hearing loss
View approved original text

Meniere's disease is a condition characterized by symptoms such as dizziness, tinnitus, and hearing loss. This medicine helps alleviate these symptoms and improves the patient's quality of life. In particular, it reduces dizziness and tinnitus, allowing for greater comfort in daily activities. It may also be effective in preventing or delaying the progression of hearing loss. Therefore, it is used for the treatment of dizziness, tinnitus, and hearing loss caused by Meniere's disease.

Dosage and Administration

Adult dosage

Adults: The initial dose is 16 mg of betahistine hydrochloride per dose, administered orally 3 times daily with meals. The usual maintenance dose is 24 ~ 48 mg of betahistine hydrochloride daily

Precautions

This medication should not be used by patients with specific types of tumors such as adrenal tumors or pheochromocytomas. Patients who have had an allergic reaction to any component of this medication should also avoid it. Patients with a history of peptic ulcer or current active peptic ulcer, asthma patients, and those taking antihistamines should exercise special caution when using this medication. Taking this medication may cause gastrointestinal symptoms such as indigestion, diarrhea, loss of appetite, abdominal distention, nausea, vomiting, and stomach pain. Additionally, symptoms such as headache, itching, skin rash, hives, palpitations, excitement, chest pain, sweating, and temporary skin redness may occur. The effectiveness of this medication may be reduced when taken in conjunction with antihistamines, so caution is advised when using them together. The safety of this medication has not been established in pregnant women or women who may become pregnant; thus, it should only be used when the benefits of treatment outweigh the risks. The safety of this medication has not been sufficiently confirmed in children, so it should be used cautiously. Elderly individuals may have weakened body functions, so they should take it with caution, possibly reducing the dosage. Overdose may result in dry mouth, abdominal pain, drowsiness, nausea, and in severe cases, convulsions, but symptoms can fully recover with appropriate treatment. General emergency measures should be taken in case of overdose. This medication should be kept out of reach of children and stored away from direct sunlight and moisture. Additionally, transferring it to another container should be avoided as it may lead to accidents or degrade the quality of the drug.

Side effects

  • Dyspepsia
  • diarrhea
  • loss of appetite
  • abdominal bloating
  • nausea
  • vomiting
  • stomach pain
  • headache
  • itching
  • skin rash
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  • urticaria
  • palpitations
  • excitement
  • chest pain
  • sweating
  • transient erythematous rash
  • dry mouth
  • abdominal pain
  • drowsiness
  • cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that can block light, at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its effectiveness.

Appearance and packaging

Appearance

Blue rectangular tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.