Ripedin Tablet 1 mg (Risperidone)

Adult dose

The therapeutic dose of this medicine should be adjusted according to the patient's clinical condition, and the lowest effective dose possible should be administered. 1. Schizophrenia 1) Adults (1) Initial dose: Administer risperidone 1 mg orally twice daily and increase gradually. (2) Maintenance dose: Administer 1∼3 mg twice daily. Adjust appropriately according to age and symptoms. (3) No additional benefit was observed with doses of 10 mg or more daily compared with lower doses, and such doses may increase the risk of extrapyramidal symptoms. Doses of 10 mg or more daily should be administered only when the benefits to the individual patient are considered to outweigh the risks. (4) Do not administer doses of 16 mg or more daily because safety has not been established. (5) A benzodiazepine may be coadministered if additional sedation is needed. 2) Administration in special populations · Elderly patients and patients predisposed to hypotension The initial dose is 0.5 mg twice daily. Depending on the patient's condition, increase by 0.5 mg twice daily until reaching 1～2 mg twice daily. In general, increases to doses of 1.5 mg or more per dose twice daily should be made at intervals of at least 1 week. 3) Switching from another antipsychotic medicine to this medicine When medically appropriate, start this medicine while gradually reducing the dose of the existing medicine. Also, when switching from an existing depot antipsychotic medicine, when medically appropriate, start this medicine in place of the next scheduled depot injection. The need to continue concomitant antiparkinsonian medication should be reassessed regularly. 2. Agitation, aggression, or psychotic symptoms in patients with dementia of the Alzheimer type The initial dose is 0.25 mg of this medicine twice daily. If necessary, depending on the patient, the dose may be increased by 0.25 mg twice daily at intervals of at least 2 days. The optimal dose for most patients is 0.5 mg twice daily, but depending on the patient, it may be increased to 1 mg twice daily. Once the patient has reached the optimal dose, once-daily administration may also be considered. As with symptomatic treatment, the appropriateness of continued use of this medicine should be evaluated. 3. Adjunctive therapy for mania in bipolar disorder · The recommended initial dose is 2 mg of this medicine once daily. Depending on the patient, the dose may be increased by up to 1 mg daily at intervals of 24 hours or longer. The optimal dose for most patients is within the range of 2∼6 mg daily. As with symptomatic treatment, the appropriateness of continued use of this medicine should be evaluated. Renal and hepatic impairment In patients with renal or hepatic impairment, administer half the initial and maintenance doses and adjust the dose more gradually. Use this medicine with caution in these patients (see 5. General Precautions).

Child dose

1. Schizophrenia · There is limited clinical experience in children and adolescents under 15 years of age. 3. Adjunctive therapy for mania in bipolar disorder · There is limited clinical experience in children and adolescents under 15 years of age. 4. Conduct disorder and other disruptive behavior disorders - Body weight 50 kg or more The initial dose is 0.5 mg of this medicine once daily. If necessary, depending on the patient, the dose may be increased by 0.5 mg daily at intervals of at least 2 days. The optimal dose for most patients is 1 mg once daily. Depending on the patient, 0.5∼1.5 mg may be administered once daily. - Body weight less than 50 kg The initial dose is 0.25 mg once daily. If necessary, depending on the patient, the dose may be increased by 0.25 mg daily at intervals of at least 2 days. The optimal dose for most patients is 0.5 mg once daily. Depending on the patient, 0.25∼0.75 mg may be administered once daily. As with symptomatic treatment, the appropriateness of continued use of this medicine should be evaluated. · There is limited clinical experience in children under 5 years of age.

This medication should be used with special caution in elderly dementia patients as it may increase mortality rates. When elderly dementia patients take this medication along with certain diuretics, such as furosemide, the risk of mortality may be further increased; thus, the risks and benefits should be carefully evaluated before concurrent administration. This medication may increase the risk of venous thromboembolism, hence it is important to check for thrombotic risk factors and take preventive measures before and during administration. This medication contains the artificial sweetener aspartame, which may pose a risk to patients with certain genetic disorders like phenylketonuria; such patients must be informed prior to use and should take care regarding the aspartame content. This medication should not be administered to patients with certain allergic reactions or hypersensitivity, those in a state of central nervous system depression, comatose patients, patients receiving epinephrine, and those with genetic issues such as lactose intolerance. Patients with cardiovascular diseases or those who are dehydrated may experience orthostatic hypotension or hypotension when using this medication, so doses should be adjusted slowly and administered cautiously. Patients with a risk of arrhythmia or QT interval prolongation, as well as those with a history of seizures or at risk of seizures, also require caution when using this medication. Patients with liver or kidney function impairment may have slower metabolism and excretion of this medication, thus requiring a reduction in dosage and a gradual increase. Pregnant women or those who may become pregnant, as well as breastfeeding mothers, should consult with their doctor before using this medication, as it may affect the fetus or newborn. This medication can cause various side effects, especially drowsiness, dizziness, insomnia, weight gain, elevated blood sugar, and extrapyramidal symptoms; if symptoms are severe, medical advice should be sought immediately. This medication has central nervous system depressant effects; caution is required when engaging in activities that require concentration, such as driving or operating machinery. In cases of overdose, serious side effects may occur, requiring immediate emergency treatment, and as there is no antidote, supportive treatment should be administered based on the symptoms. This medication may interact with other drugs; therefore, if other medications are being taken, it is essential to inform the doctor and follow medical advice for administration. When storing, keep it in a secure place out of reach of children, and take it immediately after opening the package; it is advisable not to transfer it to another container.

Increased mortality, cerebrovascular adverse reactions, venous thrombosis, nasopharyngitis, upper respiratory tract infection, sinusitis, urinary tract infection, anemia, hypersensitivity, insomnia, anxiety, nervous hyperactivity, Parkinsonism, inability to sit still, drowsiness, dizziness, sedation, tremor, muscle spasms, somnolence, orthostatic dizziness, movement disorders, syncope, blurred vision, ear pain, orthostatic hypotension, tachycardia, hypotension, nasal congestion, respiratory distress, nosebleed, sinus congestion, nausea, constipation, dyspepsia, vomiting, diarrhea, hypersalivation, dry mouth, abdominal discomfort, abdominal pain, gastric discomfort, upper abdominal pain, rash, dry skin, dandruff, seborrheic dermatitis, hyperkeratosis, back pain, arthralgia, limb pain, urinary incontinence, ejaculation failure, fatigue, asthenia, fever, chest pain, increased blood creatinine phosphokinase, increased heart rate, pneumonia, soft tissue infection, decreased appetite, confusion, transient ischemic attack, decreased consciousness, drooling, cerebrovascular accident, conjunctivitis, hypotension, cough, runny nose, difficulty swallowing, fecal impaction, erythema, abnormal posture, joint swelling, peripheral edema, gait disturbance, dependent edema, elevated body temperature, upper respiratory tract infection, rhinitis, influenza, increased appetite, middle insomnia, lethargy, headache, stuttering, attention deficit, balance disorder, hypersomnia, palpitations, oropharyngeal pain, pulmonary congestion, itching, acne, myalgia, neck pain, nocturia, frequency of urination, galactorrhea, emotional disturbances, lethargy, chest discomfort, weight gain, increased blood prolactin, agitation, dulled affect, sleep disturbances, decreased libido, sexual dysfunction, depression, nightmares, unresponsiveness to stimuli, coordination disorders, loss of consciousness, speech disorders, sensory loss, movement disorders, generalized movement disorders, cerebral ischemia, cerebrovascular accident disorders, neuroleptic malignant syndrome, diabetic coma, head tremors, seizures, psychomotor hyperactivity, delayed movement disorders, cerebrovascular disorders, sensory abnormalities, conjunctival hyperemia, eye discharge, eye rotation, eyelid edema, photophobia, eyelid crusting, dry eyes, increased tear flow, glare, glaucoma, visual impairment, tinnitus, dizziness, bradycardia, tachycardia, palpitations, type I atrioventricular block, left bundle branch block, right bundle branch block, heart block, flushing, conduction disorders, abnormal electrocardiogram, prolonged QT interval on ECG, supraventricular tachycardia, bradycardia, wheezing, aspiration pneumonia, voice disorders, productive cough, airway congestion, rales, respiratory disorders, nasal cavity swelling, hyperventilation, fecal incontinence, gastritis, lip swelling, cheilitis, salivary deficiency, abdominal distension, gastroenteritis, tongue swelling, toothache, skin discoloration, skin lesions, skin disorders, erythematous rash, papular rash, generalized rash, papulopustular rash, eczema, musculoskeletal chest pain, joint stiffness, muscle weakness, rhabdomyolysis, urination disorders, amenorrhea, gynecomastia, vaginal discharge, erectile dysfunction, ejaculation disorders, menstrual disorders, breast engorgement, sexual dysfunction, retrograde ejaculation, breast discharge, thirst, influenza-like symptoms, edema, malaise, facial swelling, discomfort, generalized edema, chills, peripheral coldness, drug withdrawal syndrome, adverse drug reactions, decreased body temperature, procedure-related pain, increased ALT, abnormal electrocardiogram, eosinophilia, increased AST, leukopenia, increased blood sugar, decreased hemoglobin, decreased hematocrit, hypothermia, low blood pressure, increased transaminases, increased gamma-glutamyl transferase, increased liver enzymes, infection, lower respiratory tract infection, gastroenteritis, subcutaneous abscess, neutropenia, hyperglycemia, hyperuricemia, hyperinsulinemia, depression, early insomnia, delusion, hallucination, depressive symptomatology, persecutory delusion, suicidal ideation, increased libido, decreased libido, sensory disturbances, tremors, psychomotor agitation, immobility, tingling, head discomfort, eyelid spasm, eye movement disorders, dizziness, bradycardia, ectopic beats, arrhythmia, hypertension, thromboembolism, postural orthostatic tachycardia syndrome, toothache, tongue spasm, excessive laxity, hemorrhoids, eczema, hyperhidrosis, drug rash, urticaria, hip pain, delayed menstruation, delayed ejaculation, infrequent menstruation, breast discomfort, breast engorgement, breast enlargement, urination difficulties, anaphylactic reaction, pain, sclerosis, falls, hypothermia, agranulocytosis, thrombocytopenia, abnormal secretion of antidiuretic hormone, diabetic ketoacidosis, diabetes, hypoglycemia, water intoxication, increased blood cholesterol, increased blood triglycerides, mania, dysgeusia, intraoperative iris hypotension syndrome, atrial fibrillation, deep vein thrombosis, pulmonary embolism, sleep apnea syndrome, intestinal obstruction, pancreatitis, jaundice, vascular edema, hair loss, neonatal drug withdrawal syndrome, urinary retention, persistent erection, hypothermia, chest pain, liver dysfunction, hepatitis, dry mouth, dry oral cavity, urinary retention, polyuria, hiccups, increased perspiration, urination disorders, leukopenia, arrhythmia, nosebleed, anemia, diarrhea, hangover, ocular movement seizures, acne, difficulty swallowing, enuresis, tic disorders, respiratory distress, suicidal ideation, cognitive disturbances, delusions, hallucinations, worsening of auditory hallucinations

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. This will help maintain the medication's efficacy for a long time.

Appearance

Oblong white film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle