Medica Ceftriaxone Injection 2g (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years: Administer 1～2 g (potency) of ceftriaxone by intravenous or intramuscular injection once daily. For serious infections or infections due to moderately sensitive pathogens, the dose may be increased to 4 g (potency) once daily. Elderly: Continue to follow the same dosage as adults without the need for changes. For gonorrhea treatment: A single intramuscular injection of 250 mg (potency) is recommended. Preventive measures before and after surgery

Child administration

Neonates (within 14 days of birth): Administer 20～50 mg (potency) per kg of body weight once daily, not exceeding 50 mg (potency) per kg. Administered irrespective of whether the infants are premature or at term. Infants and children

This medication should not be used with calcium-containing solutions. Mixing or administering it concurrently with calcium solutions can lead to precipitation of the drug and severe adverse reactions. In particular, it should never be used in conjunction with calcium solutions in neonates and premature infants as it poses significant risks. It is not to be administered to patients with hypersensitivity to this medication or with allergies to cephalosporins or penicillin antibiotics. The formulation containing lidocaine should not be given intravenously and should also not be used in premature infants or neonates with bilirubin binding issues. Patients with reduced kidney function or allergy history should use this medication cautiously, and dose adjustments or administration interval modifications may be necessary. This medication may cause side effects such as diarrhea, rash, liver dysfunction, changes in blood cell counts, so immediate consultation with healthcare professionals should occur if any unusual symptoms arise. Since severe allergic reactions or shock can occur, thorough history taking and monitoring are necessary prior to administration, and emergency care should be prepared. This medication should be administered with caution in pregnant or nursing women as it may affect the fetus or neonate, making medical judgment crucial. Elderly patients or those with compromised kidney function should be monitored closely, as the risk of bleeding may increase. Regular checks including liver and kidney function tests, and blood tests should be performed during the use of this medication, and immediate action should be taken if any abnormal findings are noted. Also, this medication can interact with other drugs, so it is essential to inform healthcare professionals of all medications being taken, especially when used with diuretics, aminoglycoside antibiotics, or vitamin K antagonists. During administration, the injection rate should be slow, and care should be taken to prevent pain or inflammation at the injection site. Finally, the prepared solution should be used as soon as possible, and care should be taken regarding temperature and duration during storage.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, breathlessness or difficulty breathing, asthma attack, respiratory issues accompanied by cough + fever, jaundice (yellowing of the skin or eyes), pronounced lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision changes, paralysis, urination problems

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• elevated liver enzymes
• headache
• dizziness
• bronchospasm
• nausea

This medication should be stored in a sealed container to prevent air ingress and kept at room temperature between 1 and 30 degrees Celsius. This storage method helps maintain the effectiveness of the medication for a longer period.

Appearance

A colorless and transparent vial containing a white to pale yellow powder

Package unit

2g*10 vials