Aklahog Syrup (Amoxicillin-Potassium Clavulanate (4:1))

Adult dosage

For mild to moderate infections such as recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin and soft tissue infections, the recommended dosage is 20 mg/5 mg of amoxicillin/potassium clavulanate per kg of body weight, divided into three doses. For severe infections such as otitis media, sinusitis, lower respiratory infections like bronchopneumonia, and urinary tract infections, the recommended dosage is 40 mg/10 mg of amoxicillin/potassium clavulanate per kg of body weight, divided into three doses.

Children's dosage

There is insufficient clinical data on the use of the 4:1 syrup for infants under 2 months of age. Therefore, it can only be used from 2 months and older, following the dosing instructions above.

This medication is a beta-lactam antibiotic and should not be used by patients with hypersensitivity to specific components or allergies to beta-lactam medications. Patients with viral diseases such as infectious mononucleosis or lymphocytic leukemia are at a high risk of rash and should avoid this medication. Patients with a history of liver dysfunction or jaundice should also be cautious due to the risk of recurrence. Patients with lactose intolerance or specific genetic metabolic disorders should not take this medication due to the lactose it contains. Patients with impaired liver or kidney function may experience increased drug concentrations, so dose adjustment and careful monitoring of intervals are necessary. Those with allergic tendencies, especially asthmatics or patients who easily develop skin rashes, should use this medication cautiously. In cases of gastrointestinal symptoms such as vomiting or diarrhea, absorption of the drug may be incomplete, requiring caution. This medication can cause gastrointestinal side effects such as diarrhea, vomiting, and abdominal pain, and serious colitis like pseudomembranous colitis can occur, making symptom monitoring important. Liver function abnormalities may rarely appear, especially more frequently reported in the elderly or men, so regular liver function tests are advised. Rarely, severe skin reactions or hypersensitivity reactions such as anaphylaxis may occur, and if symptoms such as rash, difficulty breathing, or swelling occur, the medication should be discontinued immediately and medical advice sought. Hematologic side effects such as transient blood cell reduction or bleeding tendencies may occur, necessitating attention to blood tests and bleeding symptoms. Central nervous system symptoms such as restlessness, anxiety, or seizures may rarely develop, and any unusual symptoms should be reported immediately. This medication may cause vitamin K deficiency, so patients at risk of bleeding or the elderly should be particularly careful. Women who are pregnant or breastfeeding should carefully weigh the risks and benefits of using this medication and are advised to avoid use during the first trimester of pregnancy. During breastfeeding, if the infant shows diarrhea or allergic reactions, medication should be discontinued immediately. This medication has not established safety in children, especially in newborns under 2 months of age, requiring caution. The medication can interact with other drugs, so patients should inform healthcare providers of any medications they are taking, especially when used in combination with anticoagulants or specific antibiotics. In case of overdose, gastrointestinal symptoms, kidney function abnormalities, or seizures may occur, and immediate medical assistance should be sought. When storing, keep the medication in a tightly sealed container to prevent air and moisture from entering, and for optimal effectiveness, store in a cool and dry place below 25 degrees Celsius.

Serious side effects

Urticaria, skin-mucosal syndrome (Stevens-Johnson syndrome), shock, rash, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing with bronchospasm, laryngeal edema, anaphylactic shock, jaundice, hepatitis, cholestatic jaundice, severe swelling (edema), high blood pressure, severe edema, acute renal failure, interstitial nephritis, hematuria, sudden and very severe headache, seizures, confusion, visual abnormalities

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal distension, constipation, colonic pain, acid reflux, soft stool, dry mouth, candidiasis, prolonged bleeding time and prothrombin time, mucosal candidiasis, vaginal itching, increased discharge, restlessness, anxiety, behavioral changes, confusion, drowsiness, insomnia, hyperactivity, dizziness, headache, taste alteration, fatigue, dermatitis, oral swelling

This medication should be kept in a tightly sealed container to prevent air and moisture from entering. Additionally, it is advisable to store it in a cool and dry place below 25 degrees Celsius to maintain the medication's effectiveness.

Appearance

White or pale yellow powder that is dissolved for use as a syrup

Package unit

50mL (5.0g) / bottle