Chlormycin Tablets 250mg (Clarithromycin)

Adult dosage

Adults Clarithromycin is usually administered at a dose of 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of administration is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers For 14 days, administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28). Children aged 12 years and older: Same as for adults.

Children's dosage

For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used by patients with certain medical conditions or on specific medications. For example, patients who are allergic to any ingredients in this medication or have had hypersensitivity reactions to certain antibiotics should not take it. Additionally, caution is required when used by patients with heart diseases or severely impaired liver and kidney functions. It is also safer for pregnant or breastfeeding women to avoid taking this medication. While taking this medicine, rare occurrences of severe allergic reactions, skin disorders, liver function impairment, kidney problems, and gastrointestinal disturbances can arise, so immediate medical consultation is required if symptoms appear. When taking this medication with other drugs, interactions can increase side effects or change the efficacy, so all medications being taken should be disclosed to medical staff, and a specialist's direction should be followed. Particularly, avoid co-administration with drugs that may affect heart rhythms or those that impact liver and kidney functions, or monitor them closely. Children, the elderly, and patients with weak kidney or liver functions may require dosage adjustments and should follow medical guidance. If this medication is used for a long period or repeatedly, resistant bacteria may develop, so it should only be used for the necessary duration, and treatment should be stopped when symptoms improve. If diarrhea, rash, difficulty breathing, severe abdominal pain, or jaundice symptoms occur during use, it should be discontinued immediately and a doctor consulted. This medication may affect the ability to drive or operate machinery, so caution is advised if dizziness or confusion occurs after taking it. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may arise, so the dosage must be strictly adhered to; contact a medical institution immediately in the event of an overdose. This medication should be stored in a sealed container to protect it from air and moisture, and it is best stored at room temperature between 1 to 30 degrees Celsius. This ensures the medication's effectiveness remains safe.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rashes, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, membranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, ageusia, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, parageusia, hearing loss, dysesthesia, arthralgia, myalgia, olfactory disorders, tinnitus, hearing impairment, hypoglycemia, purpuric rash, venous thrombophlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine discoloration, vasodilation, vascular edema, vasodilation, vascular edema, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, vesicular dermatitis, hyperhidrosis, papulovesicular rash, acne, Henoch-Schönlein purpura, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated blood urea, nephritis

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 to 30 degrees Celsius. This preserves the effectiveness of the medication.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle