Nepharm Injection (Nepom Hydrochloride)

Adult administration

Administer nefopam hydrochloride 20mg per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120mg per day. Administer intravenous injections slowly over 15 minutes or longer. After administration, it is advisable to have the patient lie down and rest for 15-20 minutes. If administered in an infusion solution such as electrolytes or glucose, administer 30mg over 4 hours or 40mg over 6-8 hours, proportionate to the infusion time. It is recommended to avoid mixing this medicine with other medicines for injection. Adjust the dose as appropriate according to age and symptoms.

This medication is provided in an injectable form and care should be taken when opening the glass ampule as glass fragments may mix in. This medication should not be used by patients with epilepsy, myocardial infarction, those taking certain antidepressants or MAO inhibitors, individuals with hypersensitivity, children under 15 years of age, patients with a history of seizures, those who have difficulty urinating due to urinary tract and prostate issues, and patients with angle-closure glaucoma. Particular caution should be exercised in using this medication in elderly patients, pregnant and breastfeeding women, and those taking anticholinergic medications. The use of this medication may cause decreased appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, rapid heartbeat, thirst, difficulty urinating, pain at the injection site, headache, blurred vision, fatigue, restlessness, sleep disturbances, hallucinations, drug dependence, seizures, and allergic reactions. Adverse reactions may vary depending on the dosage and most will disappear with repeated administration. This medication helps relieve inflammation and pain but is not a treatment for the underlying cause, so it should be used with consideration of the extent of acute inflammation, pain, or fever. Long-term use should be avoided, and it should be used cautiously in cases of infectious inflammation together with antibiotics or antifungals. In elderly patients, the lowest effective dose should be administered, and special attention should be given to the occurrence of side effects, as patients with impaired liver or kidney function could be affected in the metabolism and excretion of this medication. This medication may cause drowsiness or decreased behavior, so it is advisable not to take it when performing tasks that require attention such as driving or operating machinery. When combined with other analgesics or certain medications, side effects may increase, so it is essential to consult a professional. It is recommended that women who are pregnant or breastfeeding do not use this medication. Children under 15 years of age should not use this medication as its safety and efficacy have not been established. In case of overdose, immediate consultation with healthcare professionals is necessary, and appropriate treatment, including monitoring of heart and respiratory function, is required. This medication should be avoided from being mixed with other drugs for injection and stored in a sealed container to keep away from children, in a cool, dry place away from direct sunlight. Additionally, to prevent misuse, it is important not to transfer it to other containers.

• Loss of appetite
• gastrointestinal disturbance
• nausea
• drowsiness
• vomiting
• excessive sweating
• dizziness
• tachycardia
• palpitations
• thirst

This medication should be stored in a sealed container to prevent air or moisture from entering. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

A transparent glass ampule containing a colorless, transparent liquid

Package unit

1 ampule (2mL) × 50