Ilseong Ceftriaxone Injection 2 grams (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years: Administer 1–2g (based on potency) of Ceftriaxone by intravenous or intramuscular injection once daily. For infections caused by severe pathogens or pathogens showing moderate susceptibility, the dose may be increased to 4g (based on potency) once daily. Elderly patients should follow the adult dosage without modification. For the treatment of gonorrhea, a single intramuscular injection of 250mg (based on potency) is recommended. Prevention of infections before and after surgery.

Child administration

Neonates (within 14 days of birth): 20–50mg (based on potency) per kilogram of body weight, administered once daily but not exceeding 50mg (based on potency) per kilogram. No distinction is made between premature and normal infants. Infants and young children

This medication should not be mixed with calcium-containing solutions or other medications and should be administered separately. Particularly in neonates, the interaction of calcium and this medication may lead to precipitation and pose a risk of severe adverse reactions, thus it should not be used. It must not be administered to patients who are allergic to this drug or have had hypersensitivity reactions to cephalosporin or penicillin antibiotics. It is also considered safe not to use in neonates and infants with issues regarding bilirubin binding. Patients should be closely monitored for allergic reactions or serious side effects upon administration. Regular clinical tests such as blood, liver, and kidney function tests are required, and any abnormal symptoms should be reported to healthcare professionals immediately. This drug may affect driving and machine operation abilities, so caution is advised. Women who are pregnant or breastfeeding should consult a physician before using this medication. Caution is advised in children, especially neonates and premature infants, due to the increased risk of bilirubin encephalopathy. Elderly patients may experience more pronounced adverse reactions due to decreased bodily functions, thus dosage and administration intervals should be adjusted accordingly. This drug may interact with other medications, so it is essential to disclose any current medications being taken. When storing, the prepared solution should be used as soon as possible while paying attention to storage temperature and time.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever with severe rash, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and very severe headache, thunderclap headache, seizures, altered consciousness, vision problems, paralysis, urination

Mild side effects

Eosinophilia, leukopenia, thrombocytopenia, diarrhea, rash, increased liver enzymes, headache, dizziness, bronchospasm, nausea, vomiting, itching, hematuria, diabetes, phlebitis, pain at the injection site, fever, swelling, chills, increased serum creatinine, stomatitis, candidiasis, symptoms of vitamin K deficiency, symptoms of vitamin B group deficiency, ventricular extrasystole, sweating, flushing, palpitations, nosebleeds, hypotension, Clostridium difficile-associated diarrhea, corneal

This medication should be stored in a sealed container to prevent air and moisture, and it is best to keep it at room temperature between 1°C to 30°C. By storing it this way, the effectiveness of the drug can be maintained longer and deterioration can be avoided.

Appearance

A white to pale yellow crystalline powder filled in a colorless transparent vial

Package unit

2g/vial X 10 vials/box