Rosunex Tablet 5mg (Rosuvastatin Calcium)

Adult dosage

This medication can be taken at any time of day, regardless of meals. The initial dose is 5 milligrams once daily, and if a larger reduction in LDL cholesterol is needed, it can be adjusted to a maintenance dose. The maintenance dose is usually 10 milligrams once daily for most patients. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response, with intervals of 4 weeks or more.

Children's dosage

The usual dosage range is 5 to 20 milligrams once daily. The dose should be adjusted individually based on the recommended treatment goals for each patient, with intervals of 4 weeks or more between adjustments.

This drug should not be used in certain patients. For example, patients who are allergic to this drug, have severely impaired liver function, have muscle disease, or have greatly reduced kidney function should not use this medication. Additionally, it is recommended that pregnant or breastfeeding women, and fertile women not using adequate contraception avoid this medication. Patients at high risk for myopathy or rhabdomyolysis, such as those with moderate to severe renal dysfunction, hypothyroidism, a family history or those who are alcoholics should also avoid high doses of this medication. This drug can affect liver function, so patients with a history of liver disease or heavy alcohol consumption should undergo liver function tests before administration and regularly monitor liver enzymes during treatment. If symptoms such as muscle pain or weakness appear, healthcare professionals should be notified immediately, and blood tests may be necessary to check for muscle damage. Furthermore, this medication may slightly increase blood glucose levels; thus, patients at risk for diabetes should regularly check their blood glucose and HbA1c levels. This drug may interact with other medications, especially when taken with certain antiviral agents, immunosuppressants, antibiotics, and fibrate-class drugs, so caution is warranted. When used in combination, the risk of muscle-related adverse reactions may increase, so consultation with healthcare professionals is advised. During pregnancy or breastfeeding, it is safest not to use this medication, and women of childbearing age must use proper contraceptive methods. In cases of overdose, as there is no specific antidote, treatment should be symptomatic, and monitoring of liver function and muscle enzyme levels is necessary. Dizziness may occur when driving or operating machinery, so caution is required. Finally, this medication may rarely cause serious skin reactions, liver function abnormalities, or muscle damage in some patients; any unusual symptoms should be reported to healthcare professionals immediately, and treatment should be discontinued.

Serious side effects

Rash, allergic reactions including angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, thrombocytopenia, jaundice, hepatitis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, hematuria, edema, dyspnea, ocular myasthenia, severe myasthenia, fatal and non-fatal liver failure, acute kidney failure, oliguria.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• fatigue

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. It is advised to maintain the storage temperature between 1°C and 30°C.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle