Seatil Tablet (Cefuroxime Axetil)

Adult dose

For optimal absorption, take after meals. Adults and children aged 12 years and older - Most infections: 250mg per dose twice daily. Adults and children aged 12 years and older - Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by organisms with low susceptibility: 500mg per dose twice daily. Adults and children aged 12 years and older - Urinary tract infections: 250mg per dose twice daily. Adults and children aged 12 years and older - Uncomplicated gonorrhea: Administer 1g as a single dose. Adults and children aged 12 years and older - Lyme disease: 500mg per dose twice daily for 14 days (10~21 days). For treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medicine should be administered for 7~10 days. Patients with renal impairment: Cefuroxime is excreted mainly by the kidneys. To compensate for delayed excretion in patients with significantly impaired renal function, it is recommended that the cefuroxime dose be reduced as follows. ≥ 30 mL/min/1.73m2, T1/2 1.4 - 2.4 hours: No dose adjustment required (standard dose: 125mg-500mg per dose twice daily) 10 - 29 mL/min/1.73m2, T1/2 4.6 hours: Administer the standard single dose every 24 hours < 10 mL/min/1.73m2, T1/2 16.8 hours: Administer the standard single dose every 48 hours Patients receiving hemodialysis, T1/2 2 - 4 hours: Administer an additional standard single dose at the end of each dialysis session

Child dose

Infants and children under 12 years of age - Most infections: 125mg per dose twice daily. Otitis media in children aged 2 years and older, severe infections: 250mg per dose twice daily. Infants and children under 12 years of age - Lyme disease: 250mg per dose twice daily for 14 days (10~21 days). There is limited experience with use in infants under 3 months of age. This medicine must not be divided and is therefore not suitable for treating patients who cannot swallow tablets, such as young infants and children.

This drug is a cephalosporin antibiotic and should not be administered to patients who are allergic to this class of drugs. Caution is necessary for patients with a history of allergy to penicillin or other beta-lactam antibiotics and individuals with a family history of asthma or skin rashes. Patients with severely impaired kidney function, those who cannot take oral medications, the elderly, or those in poor overall condition should use this drug with caution due to the risk of bleeding caused by vitamin K deficiency. While taking this drug, mild gastrointestinal symptoms such as headaches, dizziness, diarrhea, nausea, and abdominal pain may occur, and rarely, serious allergic reactions such as skin rashes, hives, or anaphylaxis may happen, so it is crucial to consult a physician immediately if any unusual symptoms occur. During antibiotic use, excessive proliferation of Candida or pseudomembranous colitis may occur, so if diarrhea or abdominal pain persists, discontinue treatment and seek medical attention. This drug may cause dizziness, hence care should be taken when driving or operating machinery. Women who are pregnant or breastfeeding should use this drug with caution, and special care is necessary for children and the elderly. Concomitant use with other medications may affect kidney function, especially with diuretics or certain antibiotics, so follow medical advice closely during concurrent use. In case of overdose, convulsions may occur, so caution is required, and it should be stored out of reach of children.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• anemia
• hemoglobin decrease
• hematocrit decrease
• hemolytic anemia

This drug should be stored in a tightly closed container to prevent air from entering and should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy.

Appearance

White rectangular film-coated tablets

Package unit

50 tablets (10 tablets/PTP x 5)