Zeclor Capsule 250mg (Cefaclor Hydrate)

Adult dose

Administer 250 mg (potency) per dose every 8 hours. In cases of severe infections (like pneumonia) and infections with low susceptibility, a double dosage may be administered. For acute gonococcal urethritis, a single dose of 3 g of this drug with 1 g of probenecid may be administered.

Child dose

Administer 20 mg/kg (potency) every 8 hours based on the child’s weight. For severe infections, otitis media, and infections with low susceptibility, a dose of up to 40 mg/kg (potency) may be used, with a maximum dosage of

This drug works by binding to specific proteins and interfering with bacterial cell wall synthesis, thus killing bacteria. Before using this drug, be sure to inform your healthcare provider if you have ever experienced severe allergic reactions or shock from this drug or similar antibiotics. Caution should be exercised when administering this drug to those with a history of allergy to penicillin antibiotics or individuals who have a known proclivity for allergic reactions such as asthma or skin rashes. Patients with severely impaired kidney function, elderly patients, or those in poor nutritional status should be carefully monitored due to the risk of bleeding from Vitamin K deficiency. Patients with gastrointestinal diseases, particularly a history of colitis, also need to be cautious when using this drug. This drug may rarely cause serious skin reactions such as generalized erythema, difficulty breathing, skin rashes, hives, and in severe cases, Stevens-Johnson syndrome, so administration should be stopped immediately if any abnormal symptoms appear. Regular blood tests should be done as abnormalities such as leukopenia, anemia, and thrombocytopenia may occur. As this drug could affect liver or kidney function, it should be discontinued and appropriate measures taken if symptoms of hepatitis, jaundice, or worsening kidney function appear. Gastrointestinal issues such as diarrhea, abdominal pain, and vomiting may occur, and severe colitis can develop; if symptoms worsen, consult a physician immediately. Respiratory symptoms may include rare cases of interstitial pneumonia or eosinophilic pulmonary infiltrates; any difficulty in breathing or cough should be monitored closely. Central nervous system side effects such as anxiety, insomnia, dizziness, and hallucinations have been reported infrequently, and if such symptoms occur, you should notify your healthcare provider. This drug may cause changes in flora leading to oral conditions such as stomatitis or candidiasis, so good oral hygiene should be maintained. Additionally, this drug may induce deficiencies in Vitamins K and B complex, so caution is necessary if bleeding tendencies or neurological symptoms occur. There could also be interactions with other medications, so especially when taking probenecid, nephrotoxic drugs, anticoagulants, oral contraceptives, or some antibiotics, consult your doctor. Women who are pregnant or breastfeeding should only use this drug after consulting their doctor, as safety during these periods has not been established. Babies under 1 month should avoid this drug as its safety and efficacy have not been confirmed for this age group. Elderly patients may experience side effects more easily due to decreased physiological function, so dosage and intervals should be adjusted and taken carefully. During the use of this drug, it is important to use it for the minimum duration necessary to maintain efficacy only against susceptible bacteria to prevent the development of resistant strains. Lastly, regular blood tests and liver and kidney function tests should be performed during the administration of this drug, and it is essential to inform healthcare personnel immediately if any adverse symptoms occur.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• shock
• anaphylactic symptoms
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• liver abnormalities (including jaundice)
• acute kidney failure
• severe colitis

Mild side effects

• Generalized erythema
• vascular edema
• sensory disturbances
• syncope
• hypertension
• vasodilation
• rash
• erythema
• itching
• fever

This drug should be stored in a tightly sealed container to avoid exposure to air and moisture. It is important to maintain storage temperature between 1 and 30 degrees Celsius.

Appearance

A hard capsule with an upper purple and lower white color containing a yellowish powder.

Package unit

30 capsules/bottle, 300 capsules/bottle