Clarithromycin Tablet 250mg (Clarithromycin)

Adult dosage

Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28). Children aged 12 years and older: Same as adults.

Children's dosage

Use clarithromycin dry syrup in children under 12 years of age.

This medication should not be administered to certain patients. For example, patients with allergies to this drug or similar components, patients with heart rhythm issues or severely impaired liver and kidney function, pregnant or breastfeeding women, and patients taking certain medications should not take this medication. Moreover, patients with compromised liver function or moderate to severe renal impairment should use this medication with special caution. Elderly patients or those with heart disease should also be careful when taking this medication. This medication may cause various side effects, including allergic reactions, gastrointestinal issues, skin rashes, liver dysfunction, kidney problems, and central nervous system symptoms; thus, any unusual symptoms during administration should be reported to a healthcare professional immediately. This drug has a high potential for drug interactions, particularly with heart-related medications, drugs that affect liver metabolism, and drugs that influence blood coagulation; therefore, it is essential to follow the advice of professionals when taking them together. Pregnant or breastfeeding women should not take this medication; if it is absolutely necessary, breastfeeding should be discontinued. Children or elderly patients should pay special attention to the safety and efficacy of this medication, as dosage adjustments may be needed. Long-term use or overdose of this medication can lead to severe side effects, so it is crucial to adhere to the prescribed dosages and methods of administration. Lastly, this medication should be stored at room temperature without refrigeration and protected from direct sunlight.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, xerostomia, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, discoloration of feces, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, paresthesia, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, hepatic dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, venous thrombosis at injection site, pain at injection site, inflammation at injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, cardiac arrest, atrial fibrillation, premature contractions, palpitations, vasodilation

This medication is sensitive to light, so it should be stored in an opaque, airtight container to prevent light exposure. Additionally, it is important to keep it at room temperature between 15°C and 30°C to maintain its effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle