PME Rosuvastatin Tablets 10 mg (Rosuvastatin Calcium)

Adult dosage

This medication can be taken at any time of the day, with or without food, once daily. The initial dose is 5 mg once daily, and it can be adjusted to a maintenance dose based on therapeutic response. The maintenance dose is 10 mg once daily for most patients. The maintenance dose may be adjusted appropriately every 4 weeks or longer intervals based on LDL cholesterol levels, treatment goals, and patient response, with a maximum of 20 mg daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the usual dosage range is 5 mg to 20 mg once daily. The dosage should be adjusted based on the individual patient's treatment goals, and 4

This medication should not be administered to certain patients. For example, it should not be used in patients with a known allergy to any component of this medication, those with severely impaired liver function, or patients with muscle disorders. Additionally, pregnant or breastfeeding women, and women of childbearing age who do not use appropriate contraception should not take this medication. Patients who consume excessive alcohol or have a history of liver disease should use this medication with caution, and it is advisable to perform liver function tests before and during treatment. If symptoms of myalgia or muscle weakness occur, the patient should inform a physician immediately, and muscle enzyme levels should be assessed if necessary. This medication may interact with other drugs, so caution is needed, especially when taken with certain antivirals, immunosuppressants, antibiotics, etc. Taking this medication with certain drugs may increase its blood concentration, raising the risk of muscle damage, so consultation with a healthcare provider is essential. Pregnant or breastfeeding women should not use this medication, and women of childbearing age should ensure appropriate contraception during use. If pregnancy occurs, this medication should be discontinued immediately. In the event of overdose, there is no specific antidote; treatment should be symptomatic, and liver function and muscle enzyme tests are needed. This medication may cause dizziness, so caution is required when driving or operating machinery. It is important to consult healthcare professionals immediately if any unusual symptoms or suspected side effects occur while taking this medication.

Serious side effects

Hypersensitivity reactions including urticaria, angioedema, severe swelling, chest tightness, difficulty breathing, pallor, severe rash with fever, blisters, skin peeling, sores on mucous membranes in the mouth/eyes, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, immune-mediated necrotizing myopathy, rhabdomyolysis, polyneuropathy, severe skin adverse reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• diabetes
• itching
• rash
• myalgia
• weakness

This medication should be stored in a tightly closed container to protect it from air and moisture, ideally at room temperature between 1 degree and 30 degrees Celsius. This storage method will help maintain the medication's effectiveness over time.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle