Shubastin Tablet 5mg (Rosuvastatin Calcium)

Adult dosage

Administer 5 mg once daily as the initial dose regardless of meals. If a greater reduction in LDL cholesterol is needed, the maintenance dose may be adjusted to 10 mg once daily, and the dosage should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more. The maximum daily dose may be increased up to 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia aged 10 to 17 years, the usual dosage is 5 mg to 20 mg once daily, and the dosage should be adjusted based on the individual patient's treatment goals every 4 weeks.

This medication should not be used in certain patients. For example, patients who are allergic to any ingredient of this drug, those with severely impaired liver function, those with muscle disorders, and those taking certain immunosuppressants should not take this medication. Additionally, patients with significantly impaired renal function and women who are pregnant or breastfeeding should not use this drug. The 40 mg dosage is contraindicated in patients at high risk of muscle disorders. When using this drug, liver function and muscle condition should be periodically checked. Patients who drink large amounts of alcohol or have a history of liver disease should be more cautious, and those with hypothyroidism or nephrotic syndrome should use it only after treating the underlying condition. Symptoms such as muscle pain, muscle weakness, or cramps should be reported immediately to healthcare professionals, and the use of this drug should be discontinued if necessary. This medication contains lactose, so patients with lactose intolerance should be careful. Also, this drug may interact with various medications, so if other medications are being taken, it is essential to consult a doctor or pharmacist. Specifically, when taken with some antiviral drugs, immunosuppressants, and fibrates, the risk of muscle toxicity may increase. Women of childbearing potential should use appropriate contraception before taking this drug, and it should not be taken during pregnancy or when planning to become pregnant. Women who are breastfeeding should also avoid taking this drug and consult a doctor if they need to take it. There is no specific antidote for overdose, so treatment should be based on symptoms and management should include liver function and muscle enzyme testing. This drug is known not to significantly impact driving or machinery operation; however, since dizziness may occur, caution is advised. Finally, this medication may present higher blood levels in Asians, so careful dosage determination is needed.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, jaundice, hepatitis, severe liver damage, liver failure, difficulty breathing or shortness of breath, asthma attacks, severe muscle weakness, ocular myopathy, immune-mediated necrotizing myopathy, myopathy.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps ensure the drug's effectiveness is safely maintained.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets (15 tablets/PTP×2)