Nepofan Injection (Nepofam Hydrochloride)

Adult administration

Administer 20mg per dose intramuscularly or intravenously as nefopam hydrochloride. If necessary, repeat every 6 hours, not exceeding 120mg per day. Administer the intravenous injection slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. If administered in an infusion solution such as electrolytes or glucose, administer 30mg over 4 hours or 40mg over 6-8 hours, in proportion to the infusion time. It is recommended to avoid mixing this medicine with other medicines for injection. Adjust the dose as appropriate according to the patient's age and symptoms.

This medication is in ampule form, and care should be taken when cutting the container as glass fragments may mix in. This medication should not be used by individuals with epilepsy, those with myocardial infarction, patients taking certain antidepressants such as MAO inhibitors, anyone allergic to this medication or its ingredients, children under 15 years old, individuals with a history of seizures, those unable to urinate due to urethral or prostate problems, and glaucoma patients with increased intraocular pressure. Particular caution should be exercised when administering this medication to the elderly, pregnant or breastfeeding women, and patients taking anticholinergic medications. Possible side effects when using this medication include loss of appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, increased heart rate, thirst, urinary disturbances, injection site pain, headache, blurred vision, fatigue, irritability, insomnia, hallucinations, drug dependency, seizures, and allergic reactions. These side effects may vary depending on the dosage and usually fade gradually with repeated administration. Use this medication when inflammation or pain is severe and it is advisable to avoid long-term use. This medication is not designed to treat the underlying causes of inflammation, so it should be used along with treatment for the root cause, if possible. When using this medication for inflammation due to infection, appropriate antibiotics or antifungals should be used alongside, and the patient's condition should be closely monitored. In elderly patients, use the minimum necessary dosage cautiously and pay special attention to side effects. Patients with poor liver or kidney function may be affected in the metabolism and excretion of this medication, so caution is necessary. This medication can cause drowsiness; therefore, it is advisable to avoid use when engaging in tasks requiring attention, such as driving or operating machinery. When used with other analgesics or certain medications, side effects may increase, so consult a professional when administering in combination. The use of this medication during pregnancy or breastfeeding is not recommended. Safety and efficacy have not been established for children under 15 years old, and it should not be used in this age group. Due to its anticholinergic effects, it is not recommended for the elderly. If overdose occurs, consult a doctor or pharmacist immediately and monitor heart rate and respiration closely during treatment. It is advisable to avoid combining this medication with other medications for injection.

• Loss of appetite
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• hyperhidrosis
• dizziness
• tachycardia
• palpitations
• thirst

This medication should be stored in a sealed container to prevent air or moisture from entering, and the storage temperature should be kept between 1 degree and 30 degrees Celsius. This way of storage can safely maintain the medication's effectiveness.

Appearance

Colorless, transparent liquid in a colorless transparent glass ampule

Package unit

1 ampule (2 mL) × 10/ampule