Rosutanjett Tablets 10/20 milligrams

Adult dose

Take this medication once daily, regardless of meals. The dosage range is 10/5 mg to 10/20 mg per day. The initial recommended dose is 10/5 mg once daily. For patients requiring more significant LDL cholesterol reduction, the dosage can be adjusted. After starting treatment or adjusting the dose, check blood lipid levels at intervals of 4 weeks or longer and adjust the dosage accordingly.

This drug carries a risk of rhabdomyolysis, which can lead to severe kidney dysfunction due to rare muscle tissue damage. Patients who are at high risk of muscle damage, such as those with serious infections, hypotension, major surgery, trauma, metabolic disturbances, or uncontrolled seizures, should suspend or discontinue this medication. Patients with allergies to the active ingredient or any component of this drug, those with severe liver dysfunction, those with muscle diseases, patients taking certain immunosuppressants, those with severe kidney dysfunction, pregnant or potentially pregnant women, and breastfeeding women should not take this medication. Patients with moderate renal dysfunction at high risk for muscle damage, hypothyroidism, a history of genetic muscle disease, muscle toxicity history from other statins or fibrates, alcohol addicts, Asian patients, and those taking fibrates should use this medication with special caution. This drug contains lactose; patients with lactose intolerance or certain hereditary sugar absorption disorders should avoid taking it. If muscle pain, muscle cramps, muscle weakness, fatigue, or fever occur during treatment, contact a doctor immediately for examination, and in severe cases, discontinue the medication. Liver function abnormalities may occur, so liver function tests should be performed both before and during treatment, and if liver enzyme levels are abnormally high or symptoms of liver damage appear, the medication should be discontinued. This medication may slightly elevate blood sugar levels, but its cardiovascular disease prevention benefits outweigh this risk; therefore, patients at risk for diabetes should consult their physician before use. There may be interactions with other medications, so especially if you are taking anticoagulants, fibrates, certain antibiotics, antifungals, or immunosuppressants, you must consult with your doctor or pharmacist. Pregnant or breastfeeding women should not use this medication due to potential risks to the fetus and newborn; women of childbearing age should use appropriate contraception while taking this drug. Safety in children and adolescents has not been adequately established; therefore, it is advisable not to use it except in special cases. Elderly patients should use this medication with caution due to a higher risk of muscle damage, and patients with impaired liver or kidney function also require vigilance. In case of overdose, there is no specific antidote; therefore, treatment should be symptomatic, and liver function and muscle enzyme tests should be monitored.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin sloughing, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthmatic attacks, respiratory distress associated with cough and fever, yellowing of skin or eyes (jaundice), feeling exceptionally lethargic, sudden and severe headache, lightning headache, seizures, confusion, abnormal vision, paralysis, altered urination.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• myalgia
• edema
• increased serum bilirubin
• acneiform dermatitis
• pruritus

Store this medication in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1 degree and 30 degrees Celsius. This way of storage helps maintain the drug's effectiveness and safety.

Appearance

White to almost white round film-coated tablets

Package unit

30 tablets (15 tablets/blister × 2)