Unilova Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

This medication is administered once daily at an initial dose of 5 milligrams, regardless of meals, any time during the day. For more substantial LDL cholesterol reduction, the maintenance dose can be adjusted to 10 milligrams once daily, and can be increased up to a maximum of 20 milligrams per day based on LDL cholesterol levels and patient response, with intervals of 4 weeks or more.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the dosage is administered once daily at doses ranging from 5 milligrams to 20 milligrams. The dose should be adjusted individually according to treatment goals with intervals of 4 weeks or more.

This medication should not be administered to certain patients. For example, it should not be used in patients allergic to any ingredient of this medication, those with severe liver function problems, patients with muscle-related disorders, and those taking specific medications. Women who are pregnant, breastfeeding, or of childbearing potential should have a thorough consultation regarding the risk of pregnancy and effects on the fetus before taking this medication. It is important to regularly check liver function and muscle condition while taking this medication. Patients with a history of liver disease, those who consume excessive alcohol, have hypothyroidism, or have impaired kidney function should be especially cautious. If symptoms such as muscle pain, weakness, or cramps occur, medical personnel should be notified immediately, and this medication can be discontinued if necessary. Additionally, after intense exercise, muscle enzyme test results may be affected, so caution is required during testing. This medication can raise blood sugar levels in some patients; therefore, those at risk for diabetes should undergo regular testing related to blood sugar. There may be interactions with other medications; therefore, current medications should be disclosed to medical personnel, especially when combined with specific antiviral drugs, immunosuppressants, antifungals, and fibrate-type medications. The use of this medication is not recommended during pregnancy or breastfeeding, and women planning to become pregnant should use appropriate contraceptive methods. In case of overdose, since no specific antidote exists, treatment should follow the symptoms while monitoring liver function and muscle enzyme levels. This medication may cause symptoms such as dizziness, so caution is needed when driving or operating machinery. Finally, if severe skin rashes, fever, or systemic symptoms indicating severe skin reactions occur while taking this medication, use should be discontinued immediately, and consultation with medical personnel is required.

Serious side effects

Hypersensitivity reactions including angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, polyneuropathy, severe muscle weakness, difficulty breathing, ophthalmoplegia, jaundice, hepatitis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, acute renal failure, oliguria, chest discomfort

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• myalgia
• weakness
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

Yellow round film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, For export - 30 tablets/box [(10 tablets/PTP x 3)], For export - 100 tablets/box [(10 tablets/PTP x 10)]