Dilatril Tablets (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients For some elderly patients, 12.5 mg once daily may provide sufficient effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the standard treatment regimen already being administered (the conventional treatment regimen for chronic heart failure using ACE inhibitors, diuretics, and usually digitalis preparations) must be stable. In addition, fluid retention should be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be administered to certain patients. For example, patients who have had an allergic reaction to this drug or any of its ingredients, patients with severely impaired cardiac function, patients with very slow heart rates, patients with pulmonary disorders, and patients with severe metabolic abnormalities due to diabetes may be at risk if they take this drug. Additionally, it is advisable for pregnant or breastfeeding women to avoid taking this medication. Special caution is needed for diabetic patients, patients with a history of severe allergic reactions, patients with impaired kidney or liver function, and the elderly. Blood pressure and heart condition should be monitored frequently during treatment, and if symptoms worsen, the physician should be consulted immediately. Possible side effects such as dizziness, fatigue, headache, irregular heartbeat, gastrointestinal disorders, and skin rash may occur, so caution should be exercised. In the event of severe side effects, immediate medical attention should be sought, and regular health check-ups are necessary. This medication may worsen cardiac symptoms if discontinued suddenly, so the dosage should be gradually reduced under a physician's guidance. This drug may interact with other medications, so patients should inform their physician or pharmacist of any other medications they are taking. Caution is especially necessary when taken with antihypertensives, antidiabetic drugs, or heart-related medications. During pregnancy or breastfeeding, this medication should not be taken as it may affect the fetus or newborn. Safety and efficacy in children and adolescents have not been sufficiently established; it is advisable not to administer this drug to them. Elderly patients with decreased liver function may experience higher drug concentrations; thus, it is recommended to start with a lower dose and observe their condition closely. In case of overdose, serious symptoms such as low blood pressure, decreased heart rate, impaired cardiac function, and respiratory distress may occur, demanding immediate medical attention. This medication should be stored in a sealed container away from direct sunlight and out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disturbances
• nightmares
• psychosis

This medication may be sensitive to light, so it should be stored in a sealed, light-protected container. Additionally, it is important to keep the drug at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

White, round tablet

Package unit

100 tablets - 10 tablets/ptp, 100 tablets - 10 ptp/box