Clarithromycin Tablets 250mg (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment period is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily; for severe infections, administer 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose, 3 times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This drug should not be administered to patients with known allergies to specific ingredients or those who have had hypersensitivity reactions to certain antibiotics. It should also be avoided in patients with severe heart disease or impaired liver or kidney function, as well as in women who are pregnant or breastfeeding. This medication may interact with other drugs, so it is essential to inform your doctor about any medications you are currently taking, especially when used with drugs that can affect heart rhythm, as this can be dangerous. During treatment, allergic reactions or severe side effects may occur, so if symptoms such as difficulty breathing, rash, severe abdominal pain, diarrhea, or dizziness occur, you should consult your doctor immediately. In patients with compromised liver or kidney function, dose adjustments are necessary, and older adults should use it with caution. Long-term or high-dose use may lead to tinnitus or hearing loss, so if unusual symptoms occur, usage should be discontinued. Various side effects such as gastrointestinal disturbances, neurological issues, and skin rashes have been reported, so it is essential to monitor symptoms during use. To prevent antibiotic resistance, take the medication strictly as directed by your doctor for the specified duration and do not stop or adjust the dose arbitrarily. If you are pregnant or breastfeeding, avoid using this medication; if necessary, consult a healthcare professional before proceeding. This medication should not be administered to patients with certain genetic conditions, so it is important to confirm this in advance. Caution is required while driving or operating machinery, as dizziness or confusion may occur. In the event of an overdose, gastrointestinal symptoms or central nervous system disturbances may appear, necessitating an immediate visit to a healthcare facility. To use this medication safely, it is essential to follow your doctor's prescriptions and instructions strictly and to have a thorough understanding of potential drug interactions and side effects.

Shock, anaphylactic symptoms, shortness of breath, seizures, flushing, rash, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal ulceration, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, discoloration of the stool, membranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased serum myoglobin, increased urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, atrial fibrillation, cardiac arrest, extrasystoles, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, distension, tongue discoloration, tooth discoloration, sweating, vesiculobullous dermatitis, papulovesicular rash, acne, Henoch-Schonlein purpura, acute generalized pustular rash, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea nitrogen, phlebitis at injection site, pain at injection site, inflammation at injection site, malaise, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, changes in urine color, psychogenic disorder, state of confusion, abnormal dreams, taste distortion, reversible hearing loss, paresthesia, olfactory dysfunction, hearing loss, hypoglycemia, tinnitus, hearing impairment, hypoglycemia, changes in mental state, obsessive behavior, hypokalemia, hypoxemia

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it is important to store it at room temperature between 1 degree and 30 degrees Celsius to maintain its efficacy.

Appearance

Yellow oval film-coated tablets with a vanilla flavor

Package unit

30 tablets/bottle, 100 tablets/bottle