Pregast Capsule 150 mg (Pregabalin)

Adult dose

This medication is administered orally, divided into two doses daily, irrespective of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Starting dose of 150 mg per day; dose may be increased to 300 mg per day after 3 to 7 days, and, if necessary, may be further increased to a maximum of 600 mg per day at intervals of 7 days. - Central Neuropathic Pain: Starting dose of 150 mg per day; may be increased to 300 mg per day after one week.

Child dose

The safety and efficacy data are insufficient for children under the age of 12 and adolescents aged 12 to 17, so administration is not recommended.

This medication may increase the risk of suicidal thoughts or behaviors, so if there are mood changes or unusual behaviors during treatment, healthcare professionals should be informed immediately. Patients with hypersensitivity to this medication or lactose intolerance, or genetic disorders of lactose metabolism should not take it. Patients with diabetes should be careful as weight gain may necessitate adjustment of blood sugar control medications. If symptoms of angioedema occur, medication should be stopped immediately and caution should be taken if there is significant dizziness or drowsiness, as it may increase the risk of accidents. Blurred vision or visual changes may occur; if symptoms arise, consult a healthcare professional. Patients with a history of substance abuse may have a potential for misuse of this medication, so thorough evaluation before use is necessary. Patients with impaired kidney function may need dosage adjustments. Patients with heart disease should be cautious when taking this medication, particularly those with congestive heart failure, who should be administered with caution. Taking this medication together with opioid analgesics can increase the risk of central nervous system depression, so caution is needed when taken together. Use of this medication in early pregnancy may pose a risk of congenital malformations to the fetus, so pregnant women should avoid it, and women of childbearing age should use effective contraception. Lactating women should consider discontinuing breastfeeding or stopping the medication, as it may pass into breast milk. Caution should be exercised when engaging in hazardous activities such as driving or operating machinery, as dizziness or drowsiness may occur. If severe skin rashes or allergic reactions occur during use of this medication, it should be stopped immediately and healthcare professionals consulted. In case of overdose, symptoms like drowsiness, confusion, depression, or seizures may appear, and immediate medical attention should be sought, including possible treatments such as hemodialysis if necessary. Keep this medication out of reach of children and do not transfer it to another container.

Serious side effects

Hives, severe swelling (edema), angioedema (facial, periorbital, and upper airway swelling), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, respiratory distress, asthma attacks, respiratory issues with cough + fever, jaundice (yellowing of skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and severe.

Mild side effects

• Dizziness
• drowsiness
• confusion
• sense of orientation disturbance
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication is sensitive to air and moisture, so it must be stored in a tightly closed container. It is important to maintain a storage temperature between 15 and 30 degrees Celsius to safely preserve the efficacy of the medication.

Appearance

A hard capsule with an upper and lower white part containing a white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 60 capsules/bottle