Clarithromycin Tablets 500 mg

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medicine should not be used in certain patients. For example, patients who are allergic to the components of this medication or have had hypersensitivity reactions to specific antibiotics should avoid its use. Additionally, it is safe for patients taking medications that may affect heart rhythm, patients with severely impaired liver or kidney function, pregnant or breastfeeding women to avoid this medication. Special caution should be taken with patients who have impaired liver or kidney function, those with heart disease, elderly patients, and patients who are taking other antibiotics. When taking this medication, an allergic reaction may occur, so if symptoms such as skin rash or difficulty breathing appear, usage should be stopped immediately and consult with a healthcare professional. Gastrointestinal side effects may include nausea, vomiting, diarrhea, and abdominal pain; if severe diarrhea or abdominal pain occurs persistently, the medication should be stopped and medical attention should be sought. Serious side effects such as pneumonia, liver dysfunction, or renal impairment can occur rarely; thus, any abnormal symptoms should be reported to a healthcare professional immediately. This medication has many interactions with other drugs, increasing the risk of side effects depending on concurrently taken medications; therefore, all medications being taken should be disclosed to a healthcare professional. Particularly, caution is needed when used with heart disease medications, certain antifungals, anticoagulants, blood sugar lowering agents, and immunosuppressants. Pregnant or breastfeeding women are advised to avoid this medication, and if it is necessary to take it, they should consult a specialist. Children and the elderly have different physical functions, so careful consideration should be taken regarding dosage adjustments or whether to administer this medication. Long-term or excessive use of this medication may cause tinnitus, hearing loss, or severe allergic reactions, so prescribed dosages must be strictly followed. Dizziness or confusion may occur during driving or operating machinery while taking this medication, thus caution is required. In case of overdose, appropriate treatment such as gastric lavage may be necessary, and this medication cannot be removed by dialysis. Finally, this medication should be stored away from direct sunlight at room temperature, and refrigeration is not recommended.

• Shock
• anaphylactic symptoms
• shortness of breath
• convulsions
• flushing
• rash
• itching
• hives
• erythema
• angioedema

This medication is sensitive to light; therefore, it should be stored in a container that protects it from light, in a cool place between 15 and 30 degrees Celsius. Proper storage will maintain the drug's efficacy and safety.

Appearance

Yellow, oblong film-coated tablet

Package unit

30 tablets, 100 tablets