New Glyfield Tablet 4 mg (Glymepiride)

Adult dose

Dosing should be individually adjusted for each patient. Administer orally once per day, prior to breakfast or just before the first meal. For monotherapy, initiate with 1 mg of glymepiride and may increase by 1 mg at intervals of 1-2 weeks. Generally, the maximum dose is 4 mg, but if necessary, can be increased up to 6 mg or 8 mg. For combination therapy, administer 1 day 1 time with the first meal.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or in a comatose state. Additionally, patients who have had allergic reactions to this medication or to sulfonylureas or sulfonamide medications should not be administered this drug. There is no experience using this medication in patients with severe liver or kidney dysfunction, and in such cases, switching to insulin therapy is recommended. Women who are pregnant or may become pregnant, as well as nursing mothers, should not use this medication. Patients with severe infections, or those who have just undergone surgery, or who have serious injuries may require insulin therapy, so caution is advised. Patients with gastrointestinal disorders should be careful as they may be at risk of hypoglycemia due to food absorption disorders. This medication contains lactose and should not be administered to patients with lactose intolerance or related genetic diseases. During the first week of treatment, there is a high risk of hypoglycemia, so careful monitoring is particularly important. Elderly patients or those who cannot cooperate, nutritional state below normal or those who skip meals, patients with unbalanced exercise and carbohydrate intake are at higher risk of hypoglycemia. Those who consume large amounts of alcohol or have reduced liver and kidney function may also be more sensitive to hypoglycemia. Caution is needed in patients with other endocrine disorders or who have overdosed on medications. When taking this medication with other drugs, there may also be changes in blood glucose, so these should be reported to a doctor or pharmacist. While taking this medication, symptoms of hypoglycemia such as headache, severe hunger, nausea, fatigue, confusion, drowsiness, or decreased consciousness may occur, so care is required. Visual disturbances, gastrointestinal symptoms, liver dysfunction, blood abnormalities, and allergic reactions may rarely occur, so if any abnormal symptoms arise, medical consultation should be sought immediately. Severe hypoglycemia or allergic reactions can be life-threatening and require immediate action. This medication should be used in conjunction with dietary and exercise therapy for blood sugar control, and regular administration is important. In the event of hypoglycemia, foods containing sugar should be consumed to quickly raise blood glucose levels, as artificial sweeteners without sugar are ineffective. Blood sugar control may become difficult during stressful situations, infections, or surgery, so switching to insulin therapy may be necessary. Regular checks of blood sugar and liver function should be conducted while taking this medication, and caution is advised during driving or operating machinery. This medication can interact with other drugs, so it is essential to inform about any other medications being taken. Caution is particularly required when used alongside drugs that are metabolized in the liver or those that affect blood sugar levels. Alcohol consumption can also impact changes in blood sugar levels, so careful attention is required. Pregnant or nursing women are advised to switch to insulin therapy as this medication may affect the fetus or newborn. The safety and efficacy in children under 18 have not been established, so it is advisable not to use it. Elderly patients may experience decreased kidney function, so the dosage should be adjusted and administered with caution. In cases of overdose, severe hypoglycemia may occur, and immediate medical treatment is required, which may involve inducing vomiting, gastric lavage, or intravenous glucose administration.

Serious side effects

Hives, severe swelling (edema), itching, rash, difficulty breathing, low blood pressure, shock, anaphylaxis, angioedema, Steven-Johnson syndrome (skin and mucous membrane disorder), liver dysfunction, jaundice, hepatitis, hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, aplastic anemia, thrombocytopenic purpura

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or activity

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness and safety of the medication can be well preserved.

Appearance

Light blue rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle