Aripiprazole 15 mg Tablet (Aripiprazole)

Adult dose

1. Schizophrenia - Recommended initial dose: 10 mg or 15 mg once daily, regardless of meals. - Dose can be adjusted in the range of 10-30 mg per day, but should not be increased within 2 weeks. - Maintenance treatment: Administer for at least 3 months at the 15 mg daily dose. 2. Treatment of bipolar disorder and associated mania, mixed episodes - Recommended initial dose: 15 mg once daily; may be increased up to 30 mg based on clinical response.

Child dose

1. Schizophrenia in Adolescents (ages 13-17) - Recommended dose: 10 mg once daily. - Initial dose: Start at 2 mg, increasing to 5 mg after 2 days, and then to 10 mg after another 2 days; thereafter, increase in increments of 5 mg. 2. Bipolar

This medication may increase the risk of suicidality in children, adolescents, and young adults who have major depressive disorder or other psychiatric conditions; therefore, doctors need to carefully assess the necessity of treatment and risks. All patients taking this medication should be closely monitored for worsening depression, suicidal thoughts, and behavioral changes, especially at the beginning of treatment or when the dose is changed, and family members or caregivers should also monitor the patient closely. Patients suspected of having bipolar disorder should undergo appropriate screening prior to administration of this medication, and there is a risk of manic symptoms appearing when administered to patients with bipolar disorder. This medication can cause a serious side effect called neuroleptic malignant syndrome; if symptoms like high fever, muscle rigidity, mental status changes, or autonomic dysfunction occur, immediate medical attention should be sought. Long-term use can result in irreversible abnormal movements known as tardive dyskinesia; thus, it is recommended to use the minimum effective dose for the shortest duration, and if symptoms appear, the physician should be consulted. There may be an increased risk of stroke and death in elderly patients with dementia, so this medication is not used for treating dementia patients. This medication can raise blood sugar levels; therefore, diabetic patients should regularly check their blood sugar control status, and patients with risk factors for diabetes should be closely monitored. There is a risk of venous thromboembolism, so patients with thrombotic risk factors should evaluate risks before and during treatment and take preventive measures. Patients with hypersensitivity or lactose intolerance should not use this medication, and it should be administered cautiously to those with orthostatic hypotension, seizure history, or cognitive and motor impairments. Drowsiness or dizziness may occur while taking this medication, necessitating caution when driving or operating machinery. The ability to regulate deep body temperature may be impaired; therefore, care should be taken to avoid excessive heat exposure or dehydration. Elderly patients with dysphagia or Alzheimer’s patients are at risk for aspiration pneumonia, requiring special caution. Common side effects of this medication include nausea, vomiting, constipation, headache, dizziness, anxiety, insomnia, sedation, fatigue, appetite changes, and weight gain; patients should consult their healthcare providers if these symptoms occur. Movement disorders such as akathisia, extrapyramidal symptoms, and tremors may also occur, making it crucial to observe for abnormal symptoms. If adverse reactions are severe or persistent, the patient should consult their physician to adjust the treatment plan.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, severe skin adverse reactions, shortness of breath or trouble breathing, asthma attacks, respiratory abnormalities with cough and fever, breathing problems, yellowing of skin or eyes (jaundice), profound fatigue, liver abnormalities (jaundice), sudden

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• drowsiness

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is best stored at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

Yellow round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle