Levotizal Tablets (Levocetirizine Hydrochloride)

Adult dose

Adults: Take 1 tablet (Levocetirizine Hydrochloride 5mg) orally once a day, regardless of meals. For patients with renal impairment, adjust the dose according to creatinine clearance (CLCR). - Mild (50 ≤ CLCR < 80): 1 tablet once a day - Moderate (30 ≤ CLCR < 50): 1 tablet every other day - Severe (10 ≤ CLCR < 30): 1 tablet every three days

Child dose

Children aged 6 years and older: Take 1 tablet (Levocetirizine Hydrochloride 5mg) orally once a day, regardless of meals. Adjust as appropriate based on age and symptoms.

This medication should not be used in patients with allergic reactions to specific ingredients or those who have had hypersensitivity reactions to hydroxyzine or piperazine derivatives in the past. It should not be given to patients with severely impaired kidney function or those undergoing dialysis. Women who are pregnant or may become pregnant, and those who are breastfeeding should not take this medication. It should not be administered to infants under 1 year of age, and liquid form should be used for children under 6 years instead of tablets. Additionally, this medication contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Patients with impaired kidney or liver function, as well as the elderly, should take the medication cautiously as it may increase blood concentration. Drowsiness, fatigue, headache, and dizziness can occur while taking this medication, so caution is needed when driving or operating machinery. Gastrointestinal reactions such as nausea, vomiting, abdominal pain, or diarrhea may also occur. Rarely, allergic reactions such as arrhythmias, changes in blood cell count, rashes, or itching may occur, and if any unusual symptoms appear, consult a healthcare provider immediately. This medication may cause drowsiness, so it is advisable not to take it with alcohol or other central nervous system depressants. Patients with urinary excretion impairments should exercise caution when taking this medication. Because the safety of this medication has not been sufficiently proven in pregnant or breastfeeding women, they should avoid taking it. For children under 12 years, especially infants under 1 year, it is safest not to administer due to lack of experience in usage. Elderly patients should start at a lower dose and be closely monitored due to potential prolonged retention of the drug in the body due to reduced kidney function. Discontinuation of this medication before allergy testing will not affect the test results. In cases of overdose, symptoms such as drowsiness or agitation may occur, and as there is no specific antidote, appropriate treatment for symptoms is necessary. This medication is not removed by hemodialysis, so rapid medical attention is needed in case of overdose.

Serious side effects

• Urticaria, swelling, angioedema → severe allergic reactions
• Rash → severe skin reactions
• Difficulty breathing, bronchospasm → respiratory issues
• Hypertension → severe swelling or urination issues
• Hepatitis, elevated AST, ALT, Al-P, total bilirubin → liver issues (jaundice)

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• fatigue
• dizziness
• heaviness
• excitability
• thirst
• dry lips

This medication is sensitive to light, so it should be stored in a light-protected, tightly sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the efficacy and safety of the medication.

Appearance

Oval film-coated tablets in white or pale yellow

Package unit

30 tablets/bottle, 300 tablets/bottle