Medication info
Repregan Capsule 75 mg (Pregabalin)

Repregan Capsule 75 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›75mg / 1 tablet
Manufacturer / importer
(주)셀트리온제약
Appearance
Hard capsules with an upper reddish-brown and a lower white color containing a white powder that is white or pale yellow.
Packaging
30 capsules/bottle, 60 capsules/bottle
Approval status
Active

MFDS item code 201602889 · Approved 2016.05.24 · Insurance code 693902240

Summary

Main use
Relief of peripheral and central neuropathic pain, adjunctive treatment of partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is administered orally in divided doses twice daily, regardless of food intake. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose of 150 mg once daily may be increased to 300 mg daily after 3 to 7 days, and further increased to a maximum of 600 mg daily at 7-day intervals thereafter. - Central neuropathic pain: Starting dose is 150 mg once daily, may be increased to 300 mg daily after one week.
Child dose
The safety and efficacy data in children under the age of 12 and adolescents aged 12-17 is insufficient; therefore, administration is not recommended.

Ingredients

Manufacturer
(주)셀트리온제약

Efficacy & effects

Relief of peripheral and central neuropathic pain, adjunctive treatment of partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used for the treatment of peripheral and central neuropathic pain in adults. It also helps to alleviate the symptoms of partial seizures in patients with epilepsy and is utilized as an adjunct for epilepsy. In addition, it is applied for symptom improvement in patients with fibromyalgia. Through these therapeutic effects, pain and seizure symptoms can be effectively managed.

How to take

Adult dose

This medication is administered orally in divided doses twice daily, regardless of food intake. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose of 150 mg once daily may be increased to 300 mg daily after 3 to 7 days, and further increased to a maximum of 600 mg daily at 7-day intervals thereafter. - Central neuropathic pain: Starting dose is 150 mg once daily, may be increased to 300 mg daily after one week.

Child dose

The safety and efficacy data in children under the age of 12 and adolescents aged 12-17 is insufficient; therefore, administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so changes in mood or unusual signs of behavior should be carefully monitored during treatment. Do not use this medication if you have a hypersensitivity reaction to it or genetic issues such as lactose intolerance. Diabetic patients may need to adjust their blood sugar control medication doses due to weight gain, so caution is advised. If symptoms of angioedema occur, this medication should be stopped immediately, and elderly patients should be especially cautious during the initial phase of treatment due to increased risk of accidents from dizziness or drowsiness. Blurred vision or changes in vision may occur, so consult a doctor if these symptoms arise. Sudden discontinuation of this medication may result in withdrawal symptoms such as insomnia, headache, nausea, and anxiety, so it must be tapered off gradually according to the physician's instructions. Patients with a history of drug abuse may be at higher risk of abusing this medication, so they should consult with healthcare professionals before use. Patients with heart disease or impaired kidney function should have their doses adjusted, and caution should be taken as combining this medication with opioid analgesics may increase the risk of central nervous system depression. During early pregnancy, there may be a risk of fetal malformations, so if you are pregnant or planning to become pregnant, consult a doctor before use, and breastfeeding should be stopped or the medication discontinued since it may pass into breast milk. Avoid dangerous activities such as driving or operating machinery until dizziness or drowsiness has resolved after taking this medication. In case of overdose, symptoms such as confusion, drowsiness, and depression may appear, and treatment such as hemodialysis may be required if necessary. This medication should be stored out of reach of children, and it is safer not to transfer it to another container. If skin rash or severe allergic reactions occur during treatment, stop taking the medication immediately and inform healthcare professionals.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, facial swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin shedding, pain in mucous membranes of mouth/eyes, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory complications with cough and fever, respiratory depression, breathing problems, yellowing of the skin or eyes (jaundice)

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disturbance in spatial orientation
  • excitability
  • depression
  • feelings of well-being
  • decreased libido
  • insomnia
  • depersonalization
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  • sexual dysfunction
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination disturbances
  • equilibrium disturbances
  • memory loss
  • attention deficit
  • memory impairment
  • tremors
  • speech disturbances
  • sensory abnormalities
  • reduced sensation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, it is recommended to keep the medication in a cool place between 15 to 30 degrees Celsius.

Appearance and packaging

Appearance

Hard capsules with an upper reddish-brown and a lower white color containing a white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 60 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.