Medication info
Duresin Oral Dissolving Film 0.1mg (Desmopressin Acetate)

Duresin Oral Dissolving Film 0.1mg (Desmopressin Acetate)

Prescription medicationOral
Ingredient · strength
Desmopressin Acetate›0.1mg / 1 sheet
Manufacturer / importer
CTC Bio, Co., Ltd.
Appearance
Pink or light pink rectangular oral dissolving film
Packaging
15 films (1 film / packaged in aluminum foil X 15)
Approval status
Active

MFDS item code 201602779 · Approved 2016.05.19 · Insurance code 669501410

Summary

Main use
Treatment of primary nocturnal enuresis (ages 5 years and older) and nocturia associated with nocturnal polyuria (adults)
Who takes it
Adults · Children
Adult dose
Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Immediately after removing this drug from its individual package, place it on the tongue, allow it to dissolve, and take it without water. This drug is an orally disintegrating tablet. After it dissolves, swallow it immediately without holding it in the mouth.
Child dose
Primary nocturnal enuresis (age 5 years and older) Administer 0.2mg of desmopressin acetate orally at bedtime. The dose may be increased to 0.4mg if the effect is insufficient. Whether to continue treatment should be determined after 3 months of treatment, following a treatment-free period of at least 1 week.

Ingredients

Manufacturer
CTC Bio, Co., Ltd.

Efficacy & effects

Treatment of primary nocturnal enuresis (ages 5 years and older) and nocturia associated with nocturnal polyuria (adults)

  • Primary nocturnal enuresis
  • nocturia
  • nocturnal urinary symptoms
View approved original text

This medication is used to treat primary nocturnal enuresis in children aged 5 and older and nocturna symptoms related to nocturia in adults. It helps improve the symptom of frequent urination at night, allowing patients to have a comfortable sleep. It is effective in reducing discomfort caused by enuresis and improving the quality of daily life.

How to take

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Immediately after removing this drug from its individual package, place it on the tongue, allow it to dissolve, and take it without water. This drug is an orally disintegrating tablet. After it dissolves, swallow it immediately without holding it in the mouth.

Child dose

Primary nocturnal enuresis (age 5 years and older) Administer 0.2mg of desmopressin acetate orally at bedtime. The dose may be increased to 0.4mg if the effect is insufficient. Whether to continue treatment should be determined after 3 months of treatment, following a treatment-free period of at least 1 week.

Precautions

This medication helps regulate the body's water balance. Avoid excessive fluid intake while taking this medication. It is especially important to drink only enough water to quench your thirst in order to prevent hyponatremia or water intoxication. Certain patients should not take this medication, such as those allergic to this medication or its ingredients, those with severe heart issues, those with significantly reduced kidney function, and specific patients with diabetes insipidus. Additionally, women with hypertension, kidney disease, or those who are pregnant, as well as children and the elderly, should use this medication cautiously. Side effects such as hyponatremia, headaches, nausea, and allergic skin reactions may occur, so consult a doctor immediately if unusual symptoms arise. It is important to limit fluid intake for 1 hour before taking this medication and for 8 hours after; this time limit may be extended based on kidney function. Elderly patients aged 65 and older have a higher risk of developing hyponatremia, so sodium levels should be checked frequently through blood tests. This medication may interact with other drugs, so caution is advised when used in conjunction with tricyclic antidepressants, diuretics, corticosteroids, etc. Pregnant or breastfeeding women must consult a doctor before taking this medication, and it is recommended to discontinue breastfeeding if taking this medication. In case of overdose, symptoms such as headaches, nausea, seizures, and loss of consciousness may occur, and medical attention should be sought immediately.

Side effects

  • hyponatremia
  • water intoxication
  • coma
  • seizures
  • weight gain
  • allergic reactions
  • emotional disturbances
  • headache
  • abdominal pain
  • nausea
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  • allergic skin reactions
  • dizziness
  • peripheral edema
  • polyuria
  • thirst
  • anaphylaxis
  • malaise
  • vomiting
  • cold sensation
  • loss of consciousness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and allow for safe use.

Appearance and packaging

Appearance

Pink or light pink rectangular oral dissolving film

Package unit

15 films (1 film / packaged in aluminum foil X 15)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.