Nepokan Injection (Nefopam Hydrochloride)

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, the patient should preferably lie still and rest for 15-20 minutes. If added to an infusion solution such as an electrolyte or glucose solution, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the administration time. Mixing this medicine with other drugs for injection is not recommended. Adjust the dose as appropriate according to age and symptoms.

This drug should be opened with care to avoid glass fragments entering the injection container. This medication should not be used by patients with epilepsy or myocardial infarction, those taking specific medications, and individuals with allergies to this drug or its components. Additionally, it should not be administered to children under 15 years old, patients with a history of seizures, those with urinary difficulties due to urethra or prostate issues, and patients with certain eye conditions. Elderly patients and women who are pregnant or breastfeeding should use this medication with greater caution, especially if they are taking other anticholinergic drugs. When using this medication, side effects such as loss of appetite, nausea, drowsiness, dizziness, increased heart rate, thirst, difficulty urinating, pain at the injection site, headaches, blurred vision, fatigue, nervousness, insomnia, and hallucinations may occur. These side effects can vary with drug dosage and generally resolve over time. When used for inflammation or pain treatment, it is important to remember that the aim is to alleviate symptoms rather than treating the underlying cause. Appropriate dosing should take into consideration the severity of acute inflammation, pain, or fever, and prolonged use of the same drug should be avoided. When used for infection-related inflammation, it must be administered together with antibiotics or antifungals, and the patient's condition should be carefully monitored. For elderly patients, administration should be cautious with minimal dosing, paying special attention to side effects. Patients with poor liver or kidney function may be affected in the metabolism and excretion of this drug, requiring caution. This medication may cause drowsiness; thus, it is advisable not to use it when driving or operating machinery. Using this drug with other analgesics or specific medications may increase side effects, so it is essential to consult a professional. The use of this medication is not recommended for women who are pregnant or breastfeeding. Its safety and efficacy in children have not been established, thus it should not be used in this age group. The anticholinergic effects of this drug make it unsuitable for elderly patients. In case of overdose, immediate consultation with a doctor or pharmacist is necessary, and monitoring of heart and respiratory status should be maintained. It is recommended not to mix this drug with others for injection. When storing, keep it out of reach of children, avoid direct sunlight, and store it in a cool, dry place.

• Loss of appetite
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• hyperhidrosis
• dizziness
• tachycardia
• palpitations
• thirst

This medication should be stored in a sealed container to prevent exposure to air and moisture, ideally at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and prevent degradation.

Appearance

A transparent glass ampoule containing a colorless, transparent liquid

Package unit

2mL × 50 ampoules