Basta Tablet 10/10 (Ezetimibe, Simvastatin)

Adult dose

This medication is taken once daily in the evening without regard to meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with the generally recommended starting dose being 10/20 mg daily. Patients who have less need for LDL-cholesterol reduction may start with 10/10 mg daily. After starting treatment or adjusting the dosage, lipid levels should be checked after intervals of at least 4 weeks.

This drug may cause muscle-related side effects such as myopathy or rhabdomyolysis, so if muscle pain or weakness occurs, the patient must promptly inform their physician. The risk may increase when taking high doses or certain medications together. Patients with allergies to the components of this drug or those with liver diseases should not take it. Pregnant or breastfeeding women should not take this drug, and women planning to become pregnant should consult their physician. Furthermore, this drug should not be taken with strong CYP3A4 inhibitors such as certain antifungals, antibiotics, and antivirals. Special caution is also needed when co-administering with specific immunosuppressants or anticoagulants. Patients with liver function abnormalities or elevated liver enzymes should receive regular testing and immediately inform their physician of any unusual symptoms. Elderly patients or those with reduced renal function also require special management when taking this drug. It is advisable to avoid grapefruit juice while taking this drug, and to inform healthcare providers of this medication when starting other prescriptions. There is no specific antidote in case of overdose, and symptomatic treatment will be administered accordingly. This drug has not been adequately proven safe and effective in children, hence caution is advised when administering to pediatric patients.

Serious side effects

Urticaria, angioedema, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in mouth/eyes, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe body swelling with elevated blood pressure, anaphylaxis,

Mild side effects

• Muscle pain
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• dyspepsia
• pruritus
• rash
• weakness

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is important to store it at a cool room temperature, between 1 and 30 degrees Celsius, to maintain the drug's effectiveness.

Appearance

White to pale yellow, bilaterally convex rectangular tablet

Package unit

30 tablets (10 tablets/PTP packaging x 3)