Pregabalin Capsule 75 mg (Pregabalin)

Adult dose

This medication is taken orally, twice daily, regardless of food, with a total daily dosage divided into two doses. 1. Neuropathic Pain - Initial dose: 150 mg/day - Titration: can increase to 300 mg/day after 3 to 7 days, and can be increased to a maximum of 600 mg at 7-day intervals thereafter. 2. Epilepsy - Initial dose: 150 mg/day - Titration: can increase to 300 mg/day after one week, and can thereafter be increased to a maximum of 600 mg at 7-day intervals.

Child dose

Use in pediatric patients under 12 years of age and adolescents aged 12 to 17 is not recommended due to insufficient safety and efficacy data.

This medication may lead to mental changes such as suicidal thoughts, suicidal behaviors, and depression during treatment, so patients and their caregivers should inform healthcare professionals immediately if such symptoms occur. This medication should not be used by patients with allergies to its components or with genetic lactose intolerance issues. Diabetic patients should exercise caution, as weight gain may necessitate dose adjustments of blood sugar control medications. If symptoms of angioedema, such as swelling of the face or around the mouth occur during the treatment, the medication should be discontinued immediately. Elderly patients may experience dizziness or drowsiness, increasing their risk of falls and injuries, hence caution is necessary. Temporary blurred vision or changes in vision may occur, and if symptoms are severe, discontinuation of the medication may be helpful. Abrupt discontinuation of this medication may lead to withdrawal symptoms such as insomnia, headache, nausea, and anxiety, thus tapering should be discussed with a healthcare professional. Due to the risk of drug abuse, patients with a history of substance abuse should particularly take care when using this medication, and should report any unusual behavior to healthcare professionals. Patients with impaired kidney function may require dose adjustments. Caution is advised when used in patients with severe heart disease, as well as in older adults or patients with impaired respiratory function. This medication may cause drowsiness and dizziness; hence dangerous activities such as driving or operating machinery should be avoided until symptoms are confirmed. In early pregnancy, it may affect the fetus, so pregnant women should refrain from using it if possible, and women of childbearing age should use effective contraception. During breastfeeding, this medication may be transmitted through breast milk, and the risks and benefits of using this medication while breastfeeding should be discussed with a healthcare professional. The likelihood of pharmacokinetic interactions with other drugs is low, however, co-administration with central nervous system depressants or opioid analgesics may increase the risk of respiratory depression. In case of overdose, symptoms such as confusion, drowsiness, and depression may occur, and treatments such as hemodialysis may be required if necessary. Keep out of reach of children, and transferring to other containers can negatively affect quality, so caution is required.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Dizziness
• drowsiness
• confusion
• spatial disorientation
• irritability
• depression
• euphoria
• reduced libido
• insomnia
• depersonalization

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is safe to store it at room temperature between 15 to 30 degrees Celsius.

Appearance

Hard capsules with an upper reddish-brown and lower white color containing a white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 60 capsules/bottle