Credible Tablets 10/5 mg (Ezetimibe, Rosuvastatin Calcium)

Adult dose

Administer this medication once daily regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. In patients requiring further reduction of LDL cholesterol, dosage may be adjusted. Check lipid levels in the blood at intervals of more than four weeks after starting treatment or adjusting the dose, and the maximum daily dose may be increased up to 10/20 mg.

There is a risk of serious muscle problems with this medication, so if symptoms of muscle pain or weakness occur, notify a doctor immediately. In cases of severe infection, hypotension, major surgery or trauma, metabolic abnormalities, etc., the use of this medication may need to be temporarily halted or stopped. Patients with allergies to the components of this medication, severe liver disease, muscle disorders, severely impaired kidney function, or who are pregnant or nursing should not use this medication. Patients at high risk for myopathy or rhabdomyolysis should use this medication with caution and should have muscle enzyme levels checked before and during treatment. Patients with liver dysfunction or alcohol dependency should also be cautious when using this medication. This medication may elevate liver enzyme levels, requiring regular liver function tests before and during treatment. If symptoms such as muscle pain, muscle cramps, muscle weakness, fatigue, fever, etc., occur during the use of this medication, inform a doctor immediately, and if necessary, blood tests should be performed to check for muscle damage. This medication may interact with other drugs, so inform a doctor or pharmacist of any other medications being taken. Particularly caution is needed when used with anticoagulants, fibrates, certain antibiotics, antifungal agents, etc. Women of childbearing age must use appropriate contraception while taking this medication, and if pregnancy is confirmed, discontinue immediately. Safety in children and adolescents has not been sufficiently established, thus it is not recommended. Elderly patients are at higher risk for muscle issues and should use this medication cautiously, with dosage adjustments as necessary. There is no specific antidote for overdose, and treatment should be symptomatic with supportive care, along with liver function and muscle enzyme tests required. This medication should be kept out of the reach of children and should not be transferred to other containers for safety.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

• Headache
• arthralgia
• dizziness
• myalgia
• constipation
• nausea
• abdominal pain
• itching
• diarrhea
• fatigue

This medication should be stored in a tightly closed container to avoid contact with air or moisture, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication and ensure safety during use.

Appearance

White to nearly white round film-coated tablets

Package unit

30 tablets (10 tablets/PTP packaging x 3), 100 tablets/bottle