Donepezil 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, take 5 mg once daily before bedtime. Administer the 5 mg dose for 4-6 weeks, during which clinical responses will be assessed before escalating to 10 mg. When increasing to 10 mg, watch for gastrointestinal adverse reactions. Underweight women aged 85 or older should not exceed 5 mg per day and require careful monitoring.

Child dose

There is no experience in using this medication in children.

This medication should not be used by patients who are allergic to specific ingredients, and by pregnant or nursing women. Patients with genetic disorders related to lactose should also refrain from taking this medication. Patients with heart disease should use this medication cautiously as it may affect heart rhythm. Patients with a history of peptic ulcer or those taking non-steroidal anti-inflammatory drugs should be careful of the risk of gastrointestinal bleeding. Patients with a history of asthma or lung disease should use this medication carefully as it may worsen respiratory symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should be cautious as symptoms may worsen. While taking this medication, various side effects such as cardiac abnormalities, gastrointestinal bleeding, liver dysfunction, cerebrovascular issues, and muscular problems may occur; thus, consult a healthcare professional immediately if any symptoms arise. Be careful as symptoms such as dizziness or drowsiness may occur when driving or operating machinery. If taken with other medications, interactions may occur, and you must inform healthcare professionals about your medications. Pregnant or nursing women are advised to avoid using this medication, and if it is necessary, consult a specialist. Safety for children has not been established, so this medication should not be used in children. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, or respiratory depression may occur; thus, prescribed dosages should be strictly adhered to, and immediately visit a hospital in case of excessive intake. This medication should be stored in a tightly sealed container to prevent air exposure, at a temperature between 1 to 30 degrees Celsius. This is a method to maintain the drug's efficacy and prevent degradation.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures, intracerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunctions, ataxia, dystonia, tremors, involuntary movements, gait disturbances, speech disorders), neuroleptic malignant syndrome (stupor, extreme rigidity, dysphagia, tachycardia, blood pressure variability, sweating, etc.)

Mild side effects

• Headache
• dizziness
• insomnia
• diarrhea
• vomiting
• loss of appetite
• fatigue
• muscle pain
• rash
• itchiness

This medication should be stored in a tightly sealed container to prevent air ingress and should be kept at room temperature between 1 and 30 degrees Celsius. This is a method to maintain the drug's efficacy and prevent degradation.

Appearance

White, round, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle