Vaisib Tablet 10/20 Milligrams

Adult dose

This medication should be taken once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg per day. The generally recommended starting dose is 10/20 mg once daily. Patients with less need for LDL cholesterol reduction may start with 10/10 mg once daily. For patients with homozygous familial hypercholesterolemia, the recommended dosage is 10/40 mg per day.

This medication can cause serious muscle-related side effects such as myopathy and rhabdomyolysis. These side effects may manifest as muscle pain, muscle weakness, and significantly elevated creatine kinase levels in the blood. The risk is particularly greater with high doses, so dosage adjustment is crucial. This medication should not be administered to patients with poor liver function or active liver disease. Pregnant or breastfeeding women should not take this medication, and women planning to become pregnant must consult a doctor. Furthermore, caution is needed when combined with potent CYP3A4 inhibitors such as certain antifungals, antibiotics, and antivirals as the risk of muscle side effects may increase. There may also be interactions with other lipid-lowering agents, immunosuppressants, and certain anticoagulants, so patients must inform their healthcare provider of all medications they are currently taking. If symptoms of muscle pain or weakness occur during the use of this medication, patients should contact their doctor immediately, and regular blood tests should monitor muscle condition and liver function. Elderly patients or those with decreased kidney function should also use this medication with caution. Additionally, this medication may raise blood sugar levels in some patients, so those at risk for diabetes must manage their blood sugar carefully. Lastly, specific food intake such as grapefruit juice must be limited during the use of this medication, and patients should always inform their healthcare providers of this medication when starting new drugs.

Serious side effects

Hives, angioedema, anaphylaxis, severe allergic reactions, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe skin adverse reactions, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, breathing problems, shortness of breath or difficulty breathing, asthma attacks, cough with fever associated respiratory problems, liver abnormalities (jaundice), yellowing of the skin or eyes, severe body reaction

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• abdominal pain
• nausea
• constipation

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture, and it is safest to keep it at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the drug's efficacy and prevents degradation.

Appearance

White to off-white, bilaterally convex, rectangular tablet

Package unit

30 tablets/Alu-Alu