Medication info
Duresin Oral Dispersible Film 0.2mg (Desmopressin Acetate)

Duresin Oral Dispersible Film 0.2mg (Desmopressin Acetate)

Prescription medicationOral
Ingredient · strength
Desmopressin Acetate›0.2mg / 1 sheet
Manufacturer / importer
CTC Bio, Inc.
Appearance
Pink or light pink rectangular oral dispersible film
Packaging
15 pieces (1 piece/Aluminum foil packaging X15)
Approval status
Active

MFDS item code 201600439 · Approved 2016.01.25 · Insurance code 669501390

Summary

Main use
Treatment of nocturia associated with nocturnal polyuria (adults) and primary nocturnal enuresis (ages 5 and older)
Who takes it
Adults · Children
Adult dose
Treatment of nocturia associated with nocturnal polyuria (adults only): Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after 1 week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at 1-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Immediately after removing this medicine from its individual package, place it on the tongue, allow it to dissolve, and take it without water. This medicine is an orally disintegrating tablet. Once it has dissolved, do not keep it in the mouth; swallow it immediately.
Child dose
Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, with treatment withheld for at least 1 week.

Ingredients

Manufacturer
CTC Bio, Inc.

Efficacy & effects

Treatment of nocturia associated with nocturnal polyuria (adults) and primary nocturnal enuresis (ages 5 and older)

  • Primary enuresis
  • nocturia
  • enuretic symptoms
View approved original text

This medication is used to treat enuretic symptoms associated with primary enuresis in children over 5 years old and nocturia in adults.

How to take

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only): Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after 1 week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at 1-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Immediately after removing this medicine from its individual package, place it on the tongue, allow it to dissolve, and take it without water. This medicine is an orally disintegrating tablet. Once it has dissolved, do not keep it in the mouth; swallow it immediately.

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, with treatment withheld for at least 1 week.

Precautions

This medication helps regulate the body's water balance. When taking this medication, it is important to avoid excessive fluid intake, especially to drink only as much water as necessary when feeling thirsty. There is a risk of developing hyponatremia (low sodium level in the blood) and water intoxication, which could lead to a coma. This medication should not be administered to patients with certain conditions, such as renal failure, heart failure, and habitual diabetes insipidus. Caution should be exercised for individuals with hypertension, chronic kidney disease, pregnant women, and the elderly; they may require close observation by a physician during treatment. This medication may cause side effects including headache, nausea, skin allergic reactions, weight gain, and seizures, so it is important to consult with a healthcare professional immediately if symptoms occur. During treatment, fluid intake should be restricted, particularly adjusting water intake for a certain period before and after administration. Regular monitoring of sodium levels in the blood is necessary to manage the risk of hyponatremia. When taking other medications, interactions may occur, so all medications being taken should be reported to the healthcare professional. Pregnant or breastfeeding women should carefully consider the potential effects on the fetus or baby before taking this medication. In case of overdose, symptoms such as headache, nausea, seizures, loss of consciousness may appear, and immediate medical attention should be sought. It is very important to precisely follow the instructions of the healthcare professional and adhere to the prescribed dosage and administration guidelines.

Side effects

  • coma
  • convulsions
  • weight gain
  • severe water intoxication
  • hyponatremia
  • allergic reactions
  • emotional disturbances
  • headache
  • abdominal pain
  • nausea
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  • allergic skin reactions
  • dizziness
  • peripheral edema
  • polyuria
  • thirst
  • anaphylaxis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to avoid exposure to air or moisture; it is recommended to store it at room temperature between 1°C to 30°C. Storing it this way helps maintain the medication's effectiveness.

Appearance and packaging

Appearance

Pink or light pink rectangular oral dispersible film

Package unit

15 pieces (1 piece/Aluminum foil packaging X15)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.