Clarithromycin Tablet 500 mg

Adult dosage

Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered concomitantly with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily for 14 days together with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients who have allergies to the additives or active ingredients of this medication, those with severe liver or kidney disease, and women who are pregnant or lactating should not take this drug. Additionally, patients with heart rhythm abnormalities or those taking certain other medications should avoid this drug. Since this medication is primarily excreted through the liver and kidneys, it should be administered cautiously to patients with liver disabilities or kidney failure. Elderly patients, those with heart disease, and patients taking other antibiotics also require careful observation. During treatment, various side effects such as allergic reactions, gastrointestinal disturbances, liver function abnormalities, kidney function decline, skin rashes, and nervous system anomalies can occur, so careful monitoring is necessary. If serious allergic reactions or skin diseases occur, discontinue administration immediately and seek appropriate treatment. This drug can interact with several other medications, so if you are taking any other drugs, it is essential to inform healthcare professionals. Pregnant or nursing women should not take this medication unless absolutely necessary and should follow the guidance of a healthcare expert. Some formulations are only suitable for children, and the safety for children under 12 years has not been sufficiently confirmed. Elderly patients may require dose adjustments due to declining kidney function. Overdosage may lead to gastrointestinal disturbances or central nervous system abnormalities, and medical treatment should be sought immediately. This drug should not be refrigerated during storage; it should be kept at room temperature away from direct sunlight. Lastly, caution is advised during driving or operating machinery as dizziness or confusion may occur while taking this medication.

Shock, anaphylactic symptoms, respiratory distress, convulsions, flushing, rash, itching, hives, mild skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, loss of appetite, constipation, change in stool color, membrane colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray findings, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized pustular psoriasis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood creatinine, elevated blood urea, renal failure, nephritis, phlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration

This medication is sensitive to light, so it must be stored in a special container that does not allow light in. Additionally, it is best to store the drug at room temperature between 15 and 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be well maintained.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets 200 tablets