Clarithromycin 500 mg Tablet

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. For patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Helicobacter pylori eradication in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication may not be suitable for certain patients. For example, individuals with allergies to the excipients of this medication or macrolide antibiotics should not be treated. Additionally, patients with heart disease or a history of prolonged QT interval, severe liver impairment, or significantly reduced kidney function may be at risk when taking this medication. It is advisable not to use this medication during pregnancy or while breastfeeding. This drug has various interactions with other medications, which may lead to serious side effects such as cardiac arrhythmias, liver function impairment, and kidney issues, so it is essential to inform your doctor or pharmacist about any current medications. During treatment, patients should carefully monitor for allergic reactions or serious side effects and discontinue use immediately if any unusual symptoms occur and consult a healthcare professional. Patients with heart disease, weak kidney or liver function, the elderly, and those taking other antibiotics should use this medication cautiously. This medication can cause various side effects including gastrointestinal disturbances, skin rashes, central nervous system symptoms, liver dysfunction, and kidney dysfunction, thus changes in symptoms should be closely monitored. Furthermore, prolonged or high-dose use may result in hearing impairment or tinnitus, so caution is necessary. To prevent the emergence of resistant bacteria, it is important to adhere strictly to the prescribed period and dosage and not to adjust or discontinue the treatment arbitrarily. Finally, this medication may cause symptoms such as dizziness or confusion, which can affect driving or operating machinery, so care should be taken if these symptoms occur.

• Shock
• anaphylactic symptoms
• difficulty breathing
• convulsions
• flushing
• rash
• itching
• hives
• skin flushing
• angioedema

This medication is sensitive to light, so it should be stored in a container that protects it from light. Additionally, it is important to maintain a temperature of 15 to 30 degrees Celsius during storage. Avoid storing in excessively hot or cold places for safe storage.

Appearance

Yellow oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle