Shubastin Tablet 20 Milligrams (Rosuvastatin Calcium)

Adult dosage

Can be administered at any time of day regardless of meals. The initial dose is 5 milligrams once daily and can be adjusted to a maintenance dose to achieve further LDL cholesterol reduction as needed. The maintenance dose is typically 10 milligrams once daily, which is effective for most patients. This maintenance dose may be adjusted at intervals of 4 weeks or more based on LDL cholesterol levels, therapeutic goals, and patient response.

Children's dosage

The usual dosage range is once daily 5 milligrams to 20 milligrams. The dose is individually adjusted based on the recommended therapeutic goals for each patient. The dosage should be adjusted at intervals of 4 weeks or more.

This medication should not be administered to certain patients. For example, it should not be used in patients with an allergy to any component of this medication, those with severe liver impairment, patients with muscle disorders, patients taking certain immunosuppressants, patients with severe renal impairment, pregnant or breastfeeding women, and women of childbearing age who are not using adequate contraception. Additionally, high-dose administration is prohibited in patients at high risk for muscle disorders. Risk factors include moderate renal impairment, hypothyroidism, family history of muscle disorders, and alcohol abuse. This medication contains lactose, therefore it should not be taken by patients with lactose intolerance. Caution should be exercised in patients who consume excessive alcohol or have a history of liver disease, and regular liver function tests are recommended. If symptoms such as myalgia, muscle weakness, or cramps occur, the physician should be informed immediately, and if necessary, blood tests should be conducted to check for muscle damage. If severe muscle damage is suspected, the medication should be discontinued. In cases of acute severe illness or after surgery, or if there are severe metabolic disorders, the administration of this medication should be halted. Rarely, this medication can cause severe skin reactions or liver damage, so if any rashes, jaundice, or severe fatigue occur, treatment should be stopped immediately and a physician should be consulted. This medication may interact with various other drugs, so if other medications are being taken, it is essential to inform the physician or pharmacist. In particular, the risk of muscle damage may increase when used concurrently with certain antiviral drugs, immunosuppressants, antibiotics, and lipid-lowering agents. Women who are pregnant or planning to become pregnant should not take this medication, and if pregnancy occurs while taking it, the medication should be immediately discontinued. Nursing women should also refrain from using this medication. In case of overdose, there are no specific antidotes, so appropriate treatment and monitoring will be necessary based on the symptoms. Care should be taken when driving or operating machinery as dizziness may occur. This medication may exhibit higher plasma concentrations in Asian individuals, hence dosage adjustments may be necessary. It is important to regularly check liver function and muscle-related tests for abnormalities while taking this medication.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptoms induced drug reaction syndrome (DRESS), rhabdomyolysis, severe myopathy, oculomotor palsy, acute renal failure, oliguria, jaundice, hepatitis, severe allergic reactions, severe skin abnormal reactions, dyspnea, liver abnormalities (jaundice), severe neurological symptoms, severe edema or urinary abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle