The Plus Tablet 5 mg (Tadalafil)

Adult dose

Do not crush this medicine. Take one tablet whole. For oral administration. Erectile dysfunction: Use in adult men. For patients who are expected to use tadalafil frequently (at least 2 times per week), the recommended dose is up to 5mg once daily, taken at approximately the same time each day. The suitability of continuous daily dosing should be reassessed periodically. Once-daily use for benign prostatic hyperplasia: The recommended dose of this medicine for once-daily use is 5mg, taken at approximately the same time each day. Once-daily use for erectile dysfunction and benign prostatic hyperplasia: The recommended dose of this medicine for once-daily use is 5mg, taken at approximately the same time each day, regardless of the timing of sexual activity. Use in elderly men: No dosage adjustments are necessary in elderly patients. Use in men with renal impairment - erectile dysfunction: No dose adjustment is necessary in patients with mild to moderate renal impairment. Once-daily tadalafil is not recommended for patients with severe renal impairment.[Refer to Precautions for Use 3.2) and Pharmacokinetic Properties 11.2)]. Use in men with renal impairment - benign prostatic hyperplasia: No dose adjustment is necessary in patients with mild renal impairment. Once-daily tadalafil is not recommended for patients with severe renal impairment. [Refer to Precautions for Use 3.3) and Pharmacokinetic Properties 11.2)]. Use in men with hepatic impairment: Once-daily dosing has not been evaluated in patients with hepatic impairment. Therefore, if prescribing this medicine, the physician should carefully assess the individual benefit/risk.(Refer to section 11.<Special Populations>) Use in men with diabetes: No dose adjustment is necessary in patients with diabetes.

Child dose

This medicine should not be used in persons under 18 years of age.

This medication is used for the treatment of erectile dysfunction and benign prostatic hyperplasia. Before taking this medication, the causes and conditions of erectile dysfunction or prostatic hyperplasia should be accurately assessed by a healthcare professional. Sexual activity can put strain on the heart; hence, patients with heart disease should consult their doctor before taking this medication. If any heart-related symptoms occur during sexual activity, sexual activity should be immediately stopped and the doctor should be informed. If an erection lasts longer than 4 hours after taking this medication, immediate medical assistance should be sought. If an erection lasts longer than 6 hours, there is a risk of penile tissue damage and permanent loss of erectile function. Taking this medication with nitrate products can cause a rapid drop in blood pressure, so patients on nitrates should not use this medication. Patients who have had recent severe cardiovascular diseases such as myocardial infarction, angina, or stroke should not take this medication. Additionally, it is not recommended for patients with genetic retinal diseases. This medication is also considered safe when not used in conjunction with other erectile dysfunction treatments, and patients with lactose intolerance should avoid taking it. Patients with anatomical abnormalities of the penis or certain blood disorders should use this medication with caution. Patients with severe kidney or liver dysfunction should also exercise caution when taking it. When taken with antihypertensive medications, careful dosage adjustment is required as it may lead to excessive blood pressure drop, so consult with a doctor regarding dosage adjustments. Since this medication is primarily metabolized in the liver, dosage adjustment may be necessary for patients with compromised liver function. Furthermore, it is important to note that the concentration of the medication may increase if taken with certain antibiotics or antifungal drugs. This medication is not intended for use in pregnant or nursing women or in children. Side effects such as headache, indigestion, back pain, muscle pain, flushing, limb pain, rhinitis, upper respiratory infection, cough, diarrhea, gastroesophageal reflux disease, abdominal pain, dizziness, facial flushing, itching, paresthesia, drowsiness, vertigo, anemia, anxiety, sleep disturbances, nausea, vomiting, malaise, fatigue, pain, peripheral edema, thrombocytopenia, increased blood urea nitrogen, eye pain, increased tearing, eyelid swelling, and conjunctivitis may occur during use. Dizziness or symptoms of orthostatic hypotension may occur after taking this medication, so caution is advised when driving or operating machinery. In case of overdose, immediate medical assistance should be sought, and blood dialysis does not significantly affect the elimination of this medication. Store this medication out of reach of children and it is advisable to keep it in its original packaging.

• Headache
• dyspepsia
• lumbago
• myalgia
• nasal congestion
• flushing
• limb pain
• nasopharyngitis
• upper respiratory infection
• cough

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Yellow film-coated tablet with rounded triangular shape

Package unit

30 tablets (10 tablets/PTP x 3)