Clavibo Tablets 250 Milligrams (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) per dose, 2 times daily. For severe infections, administer 500mg (potency) per dose, 2 times daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose 2 times daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine per dose, 2 times daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults Children under 12 years of age: Use clarithromycin dry syrup.

This drug should not be used in patients who are allergic to specific ingredients. In particular, patients who have had hypersensitivity reactions to similar classes of antibiotics should avoid administration. Additionally, when used in conjunction with certain heart-related medications, it may cause cardiac rhythm disturbances, so they should not be taken together. Patients with severely impaired liver or kidney function also require careful review before using this drug. It is safest not to take this medication during pregnancy or while breastfeeding. This drug can cause various side effects, including gastrointestinal disturbances, allergic reactions, liver function abnormalities, kidney function abnormalities, and central nervous system disorders, so if any unusual symptoms occur during administration, consulting a physician immediately is advised. Furthermore, there are many drug interactions, so caution is needed when co-administering with other medications, and it is essential to inform the healthcare provider of any other medications being taken. Caution and dosage adjustment are also necessary for children and elderly patients, and since there is a risk of resistant bacteria developing with prolonged use, it is crucial to take it for the exact duration as directed by a physician. Overdosage may cause gastrointestinal disturbances and central nervous system abnormalities, so the prescribed dosage must be strictly followed. This medication may cause dizziness or confusion while driving or operating machinery, so caution is necessary. Lastly, during the use of this medication, it is recommended to regularly check for abnormalities through blood tests or liver and kidney function tests.

shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increase in amylase, dysgeusia, anorexia, constipation, discoloration of stools, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increase in liver enzymes, hepatic dysfunction, liver failure, fulminant hepatitis, increase in AST, increase in ALT, increase in γ-GTP, increase in LDH, increase in ALP, increase in total bilirubin, increase in serum creatinine, increase in BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, oral ulcer, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, auditory dysfunction, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle cramps, musculoskeletal rigidity, myopathy, increased blood urea nitrogen, phlebitis at injection site, injection site pain, inflammation at injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increase in serum alkaline phosphatase, increase in serum lactate dehydrogenase, increase in international normalized ratio, prolonged prothrombin time, abnormal urine color, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, vasodilation, asthma, epistaxis, pulmonary embolism, cardiac arrest, atrial fibrillation, QT prolongation on electrocardiogram, extrasystole, palpitations, ventricular fibrillation, psychotic disorders, confusional state, non-vestibular vertigo, drowsiness, movement disorders, loss of consciousness

This drug is sensitive to light and should be stored in a special container that prevents light exposure. Additionally, it is advisable to store the medication at room temperature, between 15 to 30 degrees Celsius. This will help maintain the drug's efficacy and safety.

Appearance

Yellow oval film-coated tablets

Package unit

30 T/bottle, 200 T/bottle