Clarithromycin 500 mg Tablet

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7～14 days. For patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer for more than 14 days to these patients. ○ Mycobacterial infections: Administer 500mg (potency) per dose twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this medicine 500mg (potency) 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years or older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

It is crucial not to use this medication in certain patients. For example, patients who are allergic to any ingredient in this medication or have previously shown hypersensitivity to similar classes of antibiotics should not be administered this drug. Additionally, it may pose risks to patients with certain heart diseases or severely impaired liver and kidney functions. It is also safer for women who are pregnant or breastfeeding to avoid taking this medication. This drug has a high potential for drug interactions, so if you are already taking other medications, you must consult a doctor or pharmacist. Special caution is required when taking it with medications that may affect heart rhythm or those that are metabolized in the liver. During the use of this medication, allergic reactions or serious side effects may occur, so patients should notify medical personnel immediately if symptoms appear. Moreover, this drug can affect the balance of intestinal bacteria, and if symptoms such as diarrhea or abdominal pain persist, treatment should be discontinued, and consultation is advised. Elderly patients or those with impaired kidney or liver function may require dose adjustment and should follow a specialist's instructions. Lastly, this medication may have age-related usage restrictions for children, so pediatric patients must consult a specialist.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, dental discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, change in stool color, pseudomembranous colitis, hemorrhagic colitis, fever, cough, dyspnea, abnormal chest X-ray, increased eosinophils, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, increased eosinophils, thrombocytopenia, panhypopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, auditory impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, vasodilation, bleeding, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, dental discoloration, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue

This medication is sensitive to light, so it should be stored in a container that protects it from light. Also, it should be kept at room temperature between 15°C and 30°C, avoiding extremely hot or cold places.

Appearance

Yellow oval film-coated tablet

Package unit

28 tablets/bottle