Shubastatin 5 mg (Rosuvastatin Calcium)

Adult dose

For adults, 5 milligrams should be administered once daily at any time of the day, regardless of meals, as an initial dose. If a greater reduction in LDL cholesterol is necessary, the maintenance dose can be adjusted, with the maintenance dose being 10 milligrams once daily. Maintenance doses should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 milligrams.

Child dose

Pediatric patients aged 10 years to 17 years with heterozygous familial hypercholesterolemia are administered between 5 milligrams and 20 milligrams once daily. The dosage is adjusted according to each patient's treatment goals over intervals of 4 weeks or more.

This medication should not be used in certain patients. For example, individuals allergic to this drug, those with liver problems, and patients with muscle diseases should avoid taking it. In addition, patients with severely impaired kidney function, as well as pregnant or nursing women, should not use this drug. High-dose use is prohibited in patients at high risk for muscle disease. This drug contains lactose and caution is required for patients with lactose intolerance. It is important to regularly monitor liver function and muscle status while taking this medication. Those who drink alcohol heavily or have a history of liver disease should be particularly careful. Symptoms such as muscle pain or weakness should be reported to a doctor immediately, and the drug should be discontinued if necessary. This drug may interact with other medications, so consult a doctor or pharmacist if you are taking other medications. The risk of muscle damage may increase when used in combination with certain antiviral agents, immunosuppressants, antifungals, etc. Women who could become pregnant should employ appropriate contraceptive methods, and pregnant women should not use this drug. Nursing mothers should also avoid using this medication for safety. There is no specific antidote in case of overdose, so treatment should be based on symptoms while monitoring liver function and muscle enzyme levels. While taking this medication, dizziness or headaches may occur, so caution is needed when driving or operating machinery. Finally, this drug may show higher blood concentration levels in Asians, so dosage adjustments may be necessary. Therefore, it is extremely important to take it as directed by a physician.

Serious side effects

Allergic reactions including hives, angioedema, chest tightness, breathing difficulties, Stevens-Johnson syndrome, eosinophilia and systemic symptoms associated with drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe liver damage, severe muscle weakness, ocular myasthenia, immune-mediated necrotizing myopathy, rhabdomyolysis, severe edema associated with increased blood pressure, acute renal failure, oliguria, severe allergic reactions, severe skin reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to protect it from air or moisture, and should be kept at room temperature between 1°C and 30°C. Proper storage will help maintain the drug's effectiveness and safety.

Appearance

Yellow round film-coated tablets

Package unit

28 T / PTP