Allstatin Tablet 20 mg (Rosuvastatin Calcium)

Adult dose

The initial dose is 5 mg once daily, and if greater LDL cholesterol reduction is required, the maintenance dose can be adjusted accordingly. Most patients are managed at a maintenance dose of 10 mg once daily. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum daily dose of 20 mg.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dose range is 5 mg to 20 mg once daily. The dosage should be adjusted based on individual treatment goals.

This medicine should not be used in certain patients. For example, patients who are allergic to this medicine or have severely impaired liver function, those with muscle disorders, severe renal impairment, pregnant or breastfeeding women should not take this medicine. Additionally, high-dose administration is prohibited in patients at risk for myopathy. This medicine contains lactose, so patients with lactose intolerance should also avoid this medication. It is important to regularly monitor liver function and muscle status during use of this medicine. Particularly, patients who consume large amounts of alcohol or have a history of liver disease should be more cautious. If muscle pain or weakness occurs, immediate medical attention should be sought, and the drug should be discontinued if necessary. This medicine may interact with other drugs, so patients taking other medications should inform their doctor or pharmacist. In particular, concomitant use with certain antiviral agents, immunosuppressants, antifungals, and antibiotics may increase the risk of muscle damage. Women who are pregnant or may become pregnant should use appropriate contraception, and if pregnancy is confirmed, they must discontinue the medication immediately. It is also recommended that breastfeeding women avoid this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. This medication is known not to significantly impact driving or operating machinery; however, caution is advised as dizziness and similar symptoms may occur. Regular health check-ups and tests as directed by a physician during the use of this medication are important for safe treatment.

Serious side effects

Hypersensitivity reactions including angioedema, pancreatitis, myopathy, rhabdomyolysis, polyneuropathy, severe muscle weakness, respiratory distress, ophthalmoplegia, jaundice, hepatitis, Stevens-Johnson syndrome, eosinophilia with systemic symptoms associated with drug reaction (DRESS), immune-mediated necrotizing myopathy, edema, acute renal failure, oliguria, interstitial lung disease, fatal and non-fatal hepatic failure, severe skin reactions, severe allergic reactions.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• hives
• myalgia
• weakness

This medicine should be stored in a tightly sealed container to protect it from air and moisture. The drug should also be stored at room temperature, between 1 to 30 degrees Celsius, avoiding extremes of temperature.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle