Fabist Tablets 10mg (Rosuvastatin Calcium)

Adult dose

This medication can be taken at any time of the day, regardless of meals. The initial dose is 5 milligrams once daily. The maintenance dose is 10 milligrams once daily, and it can be adjusted based on LDL cholesterol levels, treatment goals, and patient response, typically every 4 weeks or longer. The maximum daily dose can be increased up to 20 milligrams.

Child dose

For pediatric patients aged 10 to 17 years, the dosage is administered once daily in the range of 5 milligrams to 20 milligrams. The dosage should be adjusted according to each patient's treatment goals, typically every 4 weeks or more.

This medication should not be used in certain patients. For example, patients who are allergic to this medication, have severely impaired liver function, or have a muscular disorder may be at risk if they take it. Additionally, patients with severely reduced kidney function or pregnant or breastfeeding women should also not take this medication. Women of childbearing potential should use appropriate contraceptive methods to reduce the risk of pregnancy and should only be treated after being fully aware of the risks to the fetus. Particular caution is needed for patients at high risk of muscle-related side effects. For instance, patients with moderate to severe renal impairment, hypothyroidism, or a history of genetic muscle disorders should not use high doses of this medication. Furthermore, if taken with alcohol or certain medications, the risk of muscle damage may increase. Patients with problems breaking down lactose or lactose intolerance should avoid this medication due to the lactose it contains. It is important to regularly check liver function and muscle condition while taking this medication. Patients with a history of liver disease or those who drink excessively should have liver enzyme tests before starting and during treatment. If symptoms such as myalgia, muscle weakness, or cramps occur, healthcare professionals should be notified immediately, and the medication may need to be discontinued if necessary. Blood tests to check the levels of creatine kinase (CK), an indicator of muscle damage, should be performed when such symptoms arise. Severe muscle weakness or ocular muscle weakness may occur, and if such symptoms develop, the use of this medication should be stopped immediately. This medication may interact with other drugs, particularly antiviral drugs, immunosuppressants, antibiotics, and fibrate class medications. In particular, co-administration with gemfibrozil significantly increases the risk of muscle damage, so it should be avoided. Renal function tests may be necessary for high-dose usage, and Asian patients may require dosage adjustments due to increased drug concentrations. This medication can be used in pediatric patients aged 10 to 17 years, but growth and sexual development should be monitored. While taking this medication, rare occurrences of interstitial lung disease, severe skin reactions, liver damage, neurological disorders, and blood abnormalities have been reported; patients should consult healthcare professionals if any unusual symptoms develop. Pregnant or breastfeeding individuals should not take this medication, and women who may become pregnant should use appropriate contraceptives. In the case of overdose, there is no specific antidote, and treatment should be symptomatic, including monitoring liver and muscle function. This medication does not significantly affect driving or machinery operation; however, caution is advised if symptoms such as dizziness occur. Overall, this medication can affect the liver and muscles, so regular monitoring and prompt response to unusual symptoms are essential.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, rhabdomyolysis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ocular muscle weakness, thrombocytopenia, polyneuropathy, memory loss, peripheral neuropathy, dyspnea, acute renal failure, oliguria, increased serum creatinine

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is best stored at a cool temperature below 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Pink, round film-coated tablet

Package unit

30 tablets (10 tablets/Alu-Alu) × 3