Cromycine 250 mg Tablets (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (1～14 days), and omeprazole 40mg once daily for 28 days (1～28 days).

Child dose

Children 12 years of age and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication may not be suitable for certain patients. For example, it should not be given to patients who are allergic to this medication or similar antibiotics, those with a history of cardiac arrhythmias or QT prolongation, and patients with severe liver or kidney dysfunction. Women who are pregnant or breastfeeding should not take this medication, and caution is needed when administering it to young children or patients with central nervous system infections. While taking this medication, various side effects such as rare severe allergic reactions, gastrointestinal disturbances, liver function abnormalities, kidney issues, and skin rashes may occur, so consult a physician immediately if symptoms arise. Particularly for patients with heart diseases or the elderly, there is a risk of cardiac arrhythmias due to this medication, so it should be used cautiously. This medication can interact with various other drugs, so if you are taking other medications, it is vital to inform your healthcare provider, and it is important not to use certain drugs in combination. Some patients may require dosage adjustment; therefore, if liver or kidney function is impaired, dosages and administration intervals should be adjusted according to a doctor's instructions. Long-term or high-dose use may lead to hearing loss or tinnitus, and if such symptoms appear, discontinuation of the medication and consulting with healthcare professionals is necessary. Additionally, since this medication contains lactose, patients with lactose intolerance should consult a doctor before taking it. If diarrhea or abdominal pain persists during treatment, it may be a sign of a serious intestinal condition such as pseudomembranous colitis, so inform your healthcare provider immediately. This medication may require caution during driving or operating machinery; if dizziness or confusion occurs after taking it, activities should be avoided. Lastly, to use this medication safely, it is crucial to follow the healthcare provider's instructions thoroughly and consult immediately in case of suspected side effects or unusual symptoms.

• Shock
• anaphylactic symptoms
• shortness of breath
• convulsions
• redness
• rash
• itching
• hives
• skin erythema
• angioedema

This medication should be stored in a dry place away from moisture and kept in a sealed container to prevent air from entering. It is also advisable to store it in a dark place as light may alter the drug's efficacy. The storage temperature should be maintained at room temperature, between 1 and 30 degrees Celsius.

Appearance

Yellow, oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle