Stavaster Tablet 20 mg (Rosuvastatin Calcium)

Adult dosage

For adult patients with primary hypercholesterolemia, the medication can be taken at any time during the day, independent of meals. The starting dose is 5 mg once daily, which can be adjusted as needed. The maintenance dose is usually 10 mg once daily, suitable for the majority of patients. Adjustments can be made based on LDL cholesterol levels and patient response at intervals of 4 weeks or longer. The dose can be increased to a maximum of 20 mg per day.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17), the dosage is 5 mg to 20 mg once daily. The dosage should be adjusted individually based on treatment goals.

This medication should not be used in specific patients. For example, it is contraindicated for patients with an allergy to any component of this medication, those with severe liver dysfunction, patients with muscle disorders, those taking certain immunosuppressants, patients with severely reduced kidney function, pregnant or breastfeeding women, and fertile women not using appropriate contraception. Additionally, high-dose use is prohibited in patients with a high risk of muscle disorders. This medication contains lactose, so it should not be used by patients with lactose intolerance or specific genetic metabolic disorders. Caution should be exercised in patients with liver dysfunction or excessive alcohol consumption, and it is important to regularly check liver function before and during treatment. Symptoms such as muscle pain, weakness, and damage may occur; if these symptoms appear, medical personnel should be informed immediately. Particularly, patients at high risk of muscle damage should have muscle enzyme levels checked before starting treatment, and routine monitoring through symptoms and tests is necessary during treatment. In cases of acute renal failure or severe systemic diseases, use of this medication should be discontinued. This medication may increase the risk of muscle damage when used in conjunction with other specific drugs, so if any medications are being taken concurrently, this must be disclosed to medical personnel. Using high doses of this medication may cause transient proteinuria, necessitating kidney function tests. For Asians, the drug may accumulate more in the body, so dose adjustment may be necessary. In pediatric patients aged 10 to 17, the impact on growth and secondary sexual characteristics is limited, requiring caution. During the use of this medication, rare side effects such as interstitial lung disease, severe liver damage, and severe skin reactions may occur; if symptoms appear, treatment should be discontinued immediately, and advice from medical personnel should be sought. Furthermore, this medication can raise blood sugar levels, so patients at high risk for diabetes require regular blood sugar checks. This medication can interact with many drugs, so if other medications are being taken, this should be disclosed to medical personnel, especially with particular antiviral agents, immunosuppressants, and fibrate class medications. It should be avoided during pregnancy or breastfeeding, and women who may become pregnant should use appropriate birth control methods. In case of overdose, there are no specific antidotes, and treatment should be symptomatic while monitoring liver function and muscle enzyme levels. Finally, this medication may cause dizziness, so precautions should be taken while driving or operating machinery.

Serious side effects

Allergic reactions including urticaria, angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, thrombocytopenia, jaundice, hepatitis, transaminase elevation, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, acute kidney failure, oliguria, chest tightness, dyspnea, respiratory distress, severe edema, severe allergic reactions, severe skin reactions.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is best to store it at room temperature between 1°C and 30°C, avoiding extremely hot or cold places.

Appearance

Brown round film-coated tablet

Package unit

Manufacturer packaging unit