Viewing nowCarvedilol Sustained Release Capsule 16mg (Carvedilol)
Carvedilol 16mg
Hard capsule · Prescription medication
Hanmi Pharmaceutical Co., Ltd.

MFDS item code 201404425 · Approved 2014.09.26 · Insurance code 643506990
Treatment of hypertension and angina; heart rate control in atrial fibrillation; adjunctive treatment of heart failure
This medication is used for the treatment of essential hypertension, chronic stable angina, and congestive heart failure. It is also administered as an adjunct with diuretics, digitalis preparations, ACE inhibitors, and other vasodilators to enhance therapeutic effects. It aids in heart rate control in patients with atrial fibrillation. Therefore, this drug is effectively used in the management of various cardiovascular diseases.
Administer this medicine orally with food. Do not increase the dose or discontinue treatment without a physician's instructions. Because this medicine is an extended-release formulation, do not break, crush, or chew it; swallow the capsule whole. Daily dose of conventional formulation: 3.125 mg per dose twice daily Daily dose of extended-release formulation: 8 mg per dose once daily Daily dose of conventional formulation: 6.25 mg per dose twice daily Daily dose of extended-release formulation: 16 mg per dose once daily Daily dose of conventional formulation: 12.5 mg per dose twice daily Daily dose of extended-release formulation: 32 mg per dose once daily Daily dose of conventional formulation: 25 mg per dose twice daily Daily dose of extended-release formulation: 64 mg per dose once daily Daily dose of conventional formulation: 50 mg per dose twice daily Daily dose of extended-release formulation: 128 mg per dose once daily Essential hypertension, adults: Administer 16 mg once daily for 2 days, then increase to 32mg once daily. Usually, after administering 32 mg once daily for 2 weeks, if the effect is insufficient, the dose may be increased to 64mg once daily. The maximum daily dose of this medicine is 64mg. Essential hypertension, elderly patients: Administration of 16 mg of this medicine once daily may provide a sufficient therapeutic effect. If the effect is insufficient after 2 weeks of treatment, the dose may be increased. Administer cautiously while monitoring the patient's condition. Chronic stable angina: For the first 2 days, administer 32 mg of carvedilol once daily, followed by 64 mg once daily. Chronic stable angina: Usually, administer 64 mg once daily for 2 weeks. If an increase is needed (excluding elderly patients), administer 128 mg once daily. Congestive heart failure: For initial treatment, generally administer 8 mg of carvedilol once daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 16 mg once daily for 2 weeks, then to 32 mg once daily for 2 weeks, and then to 64 mg once daily. Congestive heart failure: After taking each dose for at least 2 weeks, gradually increase the dose to the maximum dose tolerated by the patient. Congestive heart failure: The minimum effective dose of this medicine is 16 mg once daily. The maximum dose is 64 mg once daily for patients weighing 85 kg or less, and 128 mg once daily for patients weighing 85 kg or more. Heart rate control in patients with atrial fibrillation: Administer 8mg of this medicine once daily. If the effect is insufficient after 2 weeks of treatment, administer 16mg once daily. If the effect is insufficient after 2 weeks of treatment, administer 32mg once daily.
This medication should not be used in certain patients. For instance, it should not be administered to patients who are allergic to this drug, those with severely compromised heart function, patients with bradycardia, individuals with asthma or chronic lung diseases, and pregnant or nursing women. Special caution is required for diabetic patients, the elderly, patients with weakened kidney or liver function, and those with significantly low blood pressure when using this medication. In such cases, it should be administered carefully as per the physician's instructions, and the patient's condition must be monitored frequently. During treatment with this medication, symptoms such as dizziness, headaches, and fatigue may occur, and there is a risk of bradycardia or undue hypotension. In severe cases, serious issues such as heart failure or cardiac arrest may develop, so immediate medical consultation is essential if symptoms arise. There might be a worsening in liver or kidney functions, so it is important to regularly check through blood tests, etc. Additionally, sudden discontinuation of the drug may exacerbate heart-related symptoms, so it is crucial to gradually taper the dosage under a doctor's guidance. This medication can interact with other drugs, so if you are taking any other medications, please inform your physician or pharmacist. Extra caution is warranted when taken with antihypertensives, antidiabetics, antidepressants, and antiarrhythmics. It is advisable for pregnant or nursing women to avoid taking this medication, and caution is needed for the use in children and adolescents as safety has not been established. When storing the medication, keep it away from light and moisture and ensure it is out of reach of children. Avoid transferring it to another container.
Dizziness, headache, fatigue, weakness, hallucinations, confusion, depression, sleep disorders, nightmares, psychosis, bradycardia, shock, complete atrioventricular block, heart failure, cardiac arrest, hypotension, loss of consciousness, cold extremities, edema, worsening kidney function, renal failure, increased resistance in the respiratory tract, nausea, diarrhea, abdominal pain, vomiting, constipation, urticaria, itching, lichenoid reaction, allergic rash, serum aminotransferase changes, thrombocytopenia, leukopenia, hypoglycemia, masking of hyperthyroidism, hyperglycemia, weight gain, increased serum cholesterol, shortness of breath, hypertension in angina, liver dysfunction, jaundice, limb pain, decreased tears, sensory disturbances, visual disturbances, eye irritation, dry mouth, urination disorder, sexual dysfunction, allergic reactions, increased triglycerides, increased blood sugar, memory disturbance, nasopharyngitis, body tinea, soft tissue infection, chronic tonsillitis, diverticulitis, onychomycosis, sepsis, upper respiratory infection, palpitations, chest discomfort, chest pain, conjunctival injection, ligament sprain, joint swelling, pruritus, facial flushing, decreased blood pressure, increased serum uric acid, increased N-terminal brain natriuretic peptide prohormone, nausea, chest discomfort, leg edema, chest pain, cold, dry cough, cough, gastroesophageal reflux disease, acute gastritis, gastritis, gastroenteritis, food-related epigastric pain, migraine, blood pressure fluctuation, blood pressure control failure, sting, lipoma
Not everyone experiences these, and they can vary from person to person.
This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is important to store this medication at room temperature, between 1°C and 30°C, to maintain its effectiveness.
A hard capsule with red-brown upper and lower parts containing white to light yellow immediate-release and sustained-release granules.
30 capsules/bottle
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.